Publications by authors named "Bhukya Kiran Kumar"

The Covid-19 associated mucormycosis (CAM) is an emerging disease affecting immunocompromised patients. Prevention of such infections using probiotics and their metabolites persist as effective therapeutic agents. Therefore, the present study emphasizes on assessment of their efficacy and safety.

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Article Synopsis
  • * The synthesis involved -alkylation of tetrahydro-1-carbazoles, followed by a click reaction and a copper-catalyzed cycloaddition with various aromatic azides (3a-m), with the new compounds characterized by H and C NMR, mass spectroscopy, and IR spectroscopy.
  • * The compounds showed promising antimicrobial, antioxidant, and anticancer activities, particularly 4d, 4j, 4n, 4p
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Chronic metabolic disorders such as hyperglycemia (diabetes), hyperlipidemia (high cholesterol), and cancer have become catastrophic diseases worldwide. Accordingly, probiotic intervention is a new approach for alleviating catastrophic diseases. In the present study, Pediococcus pentosaceus OBK05 was investigated as a potential probiotic bacterium for antidiabetic, cholesterol-lowering, and anticancer activities by in vitro and in vivo studies.

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The present study describes the probiotic potential and functional properties of the lactic acid bacterium Pediococcus pentosaceus OBK05 isolated from buttermilk. The isolate OBK05 was assessed for its probiotic properties. The isolate showed notable tolerance to pH 2.

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The present study investigates the therapeutic and probiotic attributes of traditional Toddy Palm Nectar (TPN). Glucose was found to be the highest with 4.37 mg/ml and arabinose was the least with 2.

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Article Synopsis
  • The study evaluates 15 yeast strains from toddy palm nectar for their probiotic potential, using Saccharomyces boulardii as the control.
  • Selected strains were tested for resistance to antibiotics, tolerance to gastrointestinal conditions, and their ability to adhere to intestinal cells.
  • The two best strains were identified as Pichia kudriavzevii OBS1 and Saccharomyces cerevisiae OBS2, with OBS2 showing potential antioxidant and anticancer properties, suggesting its use as a probiotic for therapeutic applications.
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