Publications by authors named "Bhubananda Sahu"
Adv Exp Med Biol
July 2023
Article Synopsis
- Late-onset retinal degeneration (L-ORD) is a genetic eye condition caused by mutations in the CTRP5 gene, leading to macular dystrophy.
- Researchers created a new mouse model (Ctrp5 knock-out) that lacks the CTRP5 gene to investigate the disease's mechanisms more thoroughly.
- The study found that the absence of CTRP5 caused significant retinal damage and stress, including early cell changes and the buildup of harmful deposits, which supports the idea that CTRP5 is essential for maintaining healthy retinal function.
