Antioxidant Nutraceuticals: Their Adjunct Role in the Management of COVID-19 Infections and Post-COVID Syndrome.

The COVID-19 epidemic in recent years has been produced by various coronavirus strains that nearly destroyed world health policies and economics. Emerging viral strains exac-erbated the pandemic. Huge investments have been made in preventative vaccines to combat the disease, but the genetic instability of these viruses has hampered their usefulness.

Repercussion of SARS-CoV-2 on the Sexual Function in Males Updated Review.

SARS-CoV-2, also called coronavirus causes SARS-CoV-2 or severe acute respir-atory syndrome, a highly transmissible disease that has rapidly spread worldwide, straining healthcare systems and leading to a substantial number of fatalities. Interestingly, SARS-CoV-2 has revealed a gender difference, with males dying at a greater rate and with more severe cases than women. It's worth noting that the male reproductive system might be par-ticularly susceptible to damage during periods of moderate to severe sickness, which has been linked to cases of orchitis and erectile dysfunction.

Hemp fibre reinforced natural rubber bio-macromolecule based biodegradable engineered leather.

Out of the diverse industrial applications of hemp fibre, for the first time we report the development of a leather alternative (flexible composite) material by integrating hemp fibre, as a bio-reinforcement and natural rubber (latex) macromolecules, as a matrix. For developing such unique product, primarily, hemp fibre was extracted from the Canabinus sativa L., i.

Needle Tip Tracking through Photoluminescence for Minimally Invasive Surgery.

Minimally invasive surgery continues to prioritize patient safety by improving imaging techniques and tumor detection methods. In this work, an all-optical alternative to the current image based techniques for in vitro minimally invasive procedures has been explored. The technique uses a highly fluorescent marker for the surgical needle to be tracked inside simulated tissues.

A novel sensor-based digital instrument for assessment of quality of fibre extracted from banana pseudostem.

Banana () farming generates huge quantities of biomass, all of which goes to waste due to the non-availability of suitable technology for its commercial application. The potential solution to this issue could be the conversion of pseudo-stems into valuable assets by converting them into fibres for various textile and non-textile applications. The specific characteristics of banana pseudo-stem fibre i.

Formulation and evaluation of n-acetyl cysteine loaded bi-polymeric physically crosslinked hydrogel with antibacterial and antioxidant activity for diabetic wound dressing.

Diabetic wounds have become a serious global health concern, with a growing number of patients each year. Diabetic altered wound healing physiology, as well as resulting complications, make therapy difficult. Hence, diabetic wound healing necessitates a multidisciplinary strategy.

Unlocking the possibilities of therapeutic potential of silymarin and silibinin against neurodegenerative Diseases-A mechanistic overview.

Silymarin, a bioflavonoid derived from the Silybum marianum plant, was discovered in 1960. It contains C and has been extensively used as a therapeutic agent against liver-related diseases caused by alcohol addiction, acute viral hepatitis, and toxins-inducing liver failure. Its efficacy stems from its role as a potent anti-oxidant and scavenger of free radicals, employed through various mechanisms.

Unlocking the role of herbal cosmeceutical in anti-ageing and skin ageing associated diseases.

The process of skin ageing is a natural biological phenomenon characterised by the emergence of wrinkles, age spots, sagging skin, and dryness over time. The increasing significance of skin in physical attractiveness has heightened skincare concerns. Anti-ageing cosmetics play a pivotal role in nurturing the skin, enhancing its quality, and promoting overall health.

Therapeutic potential of Aloe vera-coated curcumin encapsulated nanoparticles in an Alzheimer-induced mice model: behavioural, biochemical and histopathological evidence.

Objective: The main purpose of the present study was to evaluate the therapeutic efficacy of Aloe vera-coated curcumin encapsulated nanoparticles in mitigating Alzheimer's disease progression in mice, by examining behavioural changes, biochemical markers, and histopathological alterations, thus elucidating its potential as a treatment strategy.

Methods: The green synthesis method was used to synthesise this nanoformulation, which was then characterised using a variety of techniques, including percentage encapsulation efficacy, UV-visible spectroscopy, DLS, FT-IR, FESEM, and EDX. Several assessments, including behavioural evaluations, dose optimisation studies, oxidative stress marker estimation, and histological studies, were conducted to determine the potential therapeutic impact of nanoformulation on the Alzheimer-induced mice model.

Cutting-edge Approach of Carbon Nanostructures: Targeted Drug Delivery to Central Nervous System.

Drug delivery through the blood-brain barrier (BBB) is one of the key challenges in the modern era of medicine due to the highly semipermeable characteristics of BBB that restrict the entry of various drugs into the central nervous system (CNS) for the management of brain disorders. Drugs can be easily incorporated into carbon nanocarriers that can cross the bloodbrain barrier. Numerous nanocarriers have been developed, including polymeric nanoparticles, carbon nanoparticles, lipid-based nanoparticles, etc.

Jute fibre reinforced biodegradable composites using starch as a biological macromolecule: Fabrication and performance evaluation.

The aim of this study is to develop environment friendly packaging and life style materials for replacing conventionally explored hazardous synthetic materials. The study carried out by using raw jute fibre reinforced thermoplastic corn starch (TPCS) is to develop biodegradable flexible composite materials. Flexible composites are prepared by maintaining with different fibre content (30 %, 40 % and 50 wt%).

Photoluminescence from Two-Phase Nanocomposites Embedded in Polymers.

A set of polymer-embedded, two-colored nanocomposites were prepared where the co-existing emission peaks (~578 nm and ~650 nm) had different ratios at their emission thresholds. The nanocomposite samples were simultaneously excited by a 405 nm laser, and the growth of photoluminescence intensities was studied as a function of excitation intensity. The two peaks showed different growth evolution mechanisms.

Substrate and Excitation Intensity Dependence of Saturable Absorption in Perovskite Quantum Dot Films.

Saturable absorption in perovskite quantum dot (PQD) films, leading to saturation in photoluminescence (PL), is reported. PL of drop-casting films was used to probe how excitation intensity and host-substrate influence the growth of PL intensity. The PQD films were deposited on single-crystal GaAs, InP, Si wafers and glass.

Probing shock-induced structural changes in GaSb.

Laser-driven hypervelocity impact experiments were used to study pressure-induced long-term effects on the crystal structure of undoped GaSb. X-ray diffraction and confocal micro-Raman spectra were collected on unshocked and shock-compressed samples, with corresponding pressures ranging between 8 and 23 GPa. GaSb retained bulk crystallinity at 8 GPa but showed localized site disordering, transformed into an amorphous state at 13 GPa, and stayed in that phase until 23 GPa.

Children and Adolescents with Irritable Bowel Syndrome: Treatment and Management.

Background: Irritable bowel syndrome (IBS) is a disorder that causes stomach pain in children and adolescents. It may also impact one's quality of life. IBS is linked to gastrointestinal issues such as diarrhoea and constipation.

Cyclic GAN Model to Classify Breast Cancer Data for Pathological Healthcare Task.

An algorithm framework based on CycleGAN and an upgraded dual-path network (DPN) is suggested to address the difficulties of uneven staining in pathological pictures and difficulty of discriminating benign from malignant cells. CycleGAN is used for color normalization in pathological pictures to tackle the problem of uneven staining. However, the resultant detection model is ineffective.

Microscopic description and uncertainty of the Stokes shift in semiconductors.

Using GaAs as a test material, we investigated the redshift between emission and the optical bandgap. The knowledge of the energy difference, referred to as the Stokes shift, is of considerable importance for solid-state light sources because its magnitude defines the centered monochromaticity of the emission. Employing Fan's theory, we reveal the basic parameters, which determine the Stokes shift, and provide an uncertainty analysis, considering both uncorrelated and correlated variables.

Ethylenediamine Catalyzes Nitromethane Shock-to-Detonation in Two Distinct Ways.

Adding amines to liquid nitromethane (NM) is known to lower the threshold for the shock-to-detonation transition because amines catalyze proton transfer reactions that are the initial steps in the energy release process. We studied NM with 1 wt % ethylenediamine (NM/EDA) with 4 ns input shocks using time and space resolved diagnostics: photon Doppler velocimetry (PDV), optical pyrometry, and nanosecond video imaging. The 4 ns shocks are fast enough to time-resolve the reaction kinetics and the shock-to-detonation transition.

Response of the Indian summer monsoon to global warming, solar geoengineering and its termination.

The response of the Indian Summer Monsoon (ISM) to global warming, solar geoengineering and its termination is examined using the multi-model mean of seven global climate model simulations from G2 experiment of the Geoengineering Model Intercomparison Project. Under the global warming scenario, land-ocean temperature contrasts and low-level monsoon circulation progressively strengthen accompanied by enhanced precipitation over the Indian subcontinent. Notably, in the solar geoengineered scenario, marginal surface cooling is projected over the majority of the ISM region, and there is strengthening of both upper and lower level circulation.