Publications by authors named "Bhimashankar Utage"

Background: Leishmaniasis is endemic in more than 60 countries with a large number of mortality cases. The current chemotherapy approaches employed for managing the leishmaniasis is associated with severe side effects. Therefore there is a need to develop effective, safe, and cost affordable antileishmanial drug candidates.

View Article and Find Full Text PDF

Plant originated drugs/formulations are extensively prescribed by the physicians as a complementary therapy for treating various human ailments including cancer. In this study leaves methanol extract was prepared and exposed to human breast cancer cell lines i.e.

View Article and Find Full Text PDF
Article Synopsis
  • - The study focuses on a bacteria isolated from the feces of a healthy Indian adult, identified as Enterococcus faecium (strain 17OM39), which shows promising probiotic characteristics.
  • - Strain 17OM39 demonstrates tolerance to harsh intestinal conditions, antimicrobial activity, and various beneficial traits like exopolysaccharide production and adherence to human cells.
  • - Genomic analysis revealed no harmful factors, and the strain has genes linked to producing essential nutrients and antimicrobial compounds, supporting its potential as a safe probiotic.
View Article and Find Full Text PDF

Synthesis of metal nanoparticles for improving therapeutic index and drug delivery is coming up as an attractive strategy in the mainstream of cancer therapeutic research. In the present study, curcumin-capped copper nanoparticles (CU-NPs) were evaluated as possible inhibitors of in vivo angiogenesis, pro-angiogenic cytokines involved in promoting tumor angiogenesis along with inhibition of cell proliferation and migration of breast cancer cell line MDA-MB-231. The antiangiogenic potential was assessed using in vivo chorioallantoic membrane (CAM) model.

View Article and Find Full Text PDF