Publications by authors named "Bhawna Goel"
Phytochemicals are bioactive secondary plant metabolites found in high concentrations in fruits, grains, and vegetables. Recent studies provide evidence of usage of plant-based diets rich in phytochemicals and their corelation to reduction in cancer incidence. Several phytochemicals have demonstrated effectiveness as chemotherapeutic agents against various cancers, including breast cancer.
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- - The relationship between breast cancer treatments and osteoporosis is crucial, as many therapies lower estrogen levels, increasing the risk of bone loss and triggering the need to focus on bone health during cancer treatment.
- - This review investigates how anticancer therapies lead to bone loss, exploring molecular mechanisms and the impacts of various treatments like SERMs and bisphosphonates on maintaining bone health.
- - It highlights the importance of balancing effective breast cancer treatment with bone health management, showing that bisphosphonates, denosumab, and third-generation SERMs can help reduce bone loss in patients undergoing cancer therapy.
Article Synopsis
- - Wound healing is a complex process involving interactions between the epidermis, dermis, and hypodermis, with key roles played by neutrophils and fibroblasts in inflammation and collagen production during healing phases.
- - The healing process consists of three stages: inflammation, proliferation, and remodeling, where angiogenesis and collagen production by fibroblasts are crucial for closing wounds.
- - Advanced wound dressings, including films and hydrogels, improved through polymeric materials and growth factors like PDGF, enhance healing outcomes and address challenges such as infection control and tissue regeneration.
Background: Intranasal drug delivery shows potential for brain access via olfactory and trigeminal routes.
Purpose: This work aimed to ensure brain availability of nalbuphine via the nasal route.
Method: Chitosan based nanoparticles loaded with nalbuphine were successfully prepared using ionic gelation method and characterised.