Ferroelectric Polarization and Iron Substitution Synergistically Boost Electrocatalytic Oxygen Evolution Reaction in Bismuth Oxychloride Nanosheets.

Ferroelectric materials have gained significant interest in various kinds of water splitting, but the study of ferroelectric materials for electrocatalytic water splitting is in its infancy. Ferroelectric materials have spontaneous polarization below their Curie temperature due to dipolar alignment, which results in surface charges. In 2D ferroelectric materials, spontaneous polarization depends on thickness.

Multifunctional Ultrasmall Theranostic Nanohybrids Developed by Ultrasonic Atomizer for Drug Delivery and Magnetic Resonance Imaging.

Theranostic nanoparticulate systems (TNPs) have shown potential in addressing problems related to spatial localization and temporally controlled release of drugs with the capabilities of real-time imaging to evaluate the progress of therapy. The current study reports the ultrasonic atomization-led synthesis of and evaluations of ultrasmall chitosan-based theranostic nanohybrid formulations with encapsulated doxorubicin (DOX) and iron-oxide magnetic nanoparticles. The nanohybrid particles are characterized using transmission electron microscopy, powder X-ray diffraction, FTIR, DOX encapsulation efficiency, release, cellular uptake, and toxicity.

Ultrasonic Atomizer-Driven Development of Biocompatible and Biodegradable Poly(d,l-lactide--glycolide) Nanocarrier-Encapsulated Suberoylanilide Hydroxamic Acid to Combat Brain Cancer.

The path to the discovery of anticancer drugs and investigating their potential activity has remained a quest for several decades. Suberoylanilide hydroxamic acid (SAHA), also known as "Vorinostat", is a well-known histone deacetylase inhibitor (HDACi) and has the potential to act as a therapeutic agent against tumorigenesis. Herein, we have fabricated SAHA incorporated into biocompatible and biodegradable poly(d,l-lactide--glycolide) PLGA nanoparticles (NPs) using a facile method of ultrasonic atomization and evaluated their anticancer property.

Polymeric magnetic nanoparticles: a multitargeting approach for brain tumour therapy and imaging.

The most challenging task in targeting the brain is trespassing the blood-brain barrier (BBB) which restricts the movement of about 98% small molecules. Targeting the central nervous system using magnetic nanoparticles may deliver the drug to the target site along with a contrast imaging property. The use of magnetic nanoparticles can become non-invasive drug targeting and a bio-imaging method for brain cancer.

Transitioning ABA Services From in Clinic to Telehealth: Case Study of an Indian Organization's Response to COVID-19 Lockdown.

Due to the coronavirus (COVID-19) pandemic, around the middle of March 2020, in-clinic intervention services based in applied behavior analysis provided to children had to be stopped abruptly in India. This qualitative and quantitative case study details how Behavior Momentum India (BMI), an organisation providing ABA-based interventions, transitioned services from in clinic to telehealth while continuing to target each student's skill acquisition goals in language and communication domains. A cohort of 92 students diagnosed with autism or other learning disabilities participated in this study; 51 therapists, 9 behavior supervisors, and a doctoral-level Board Certified Behavior Analyst collaborated with parents; 78% of the students and 82% of the therapists used smartphones; and only a few used iPads and laptops.

Recombinant organophosphorus hydrolase (OPH) expression in E. coli for the effective detection of organophosphate pesticides.

Accumulation and exposure of organophosphate pesticides are of great concern today owing to their abundant usage and potential health hazards. Harmful effects of organophosphate pesticide exposure and limitations of the available treatment methods necessitate the development of reliable, selective, cost-effective, and sensitive methods of detection. We developed a novel biosensor based on the enzymatic action of recombinant organophosphorus hydrolase (OPH) expressed in E.

A novel biosensor for the detection of organophosphorus (OP)-based pesticides using organophosphorus acid anhydrolase (OPAA)-FL variant.

Indiscriminate use of organophosphorus (OP)-based insecticides is a great concern to human health because of bioaccumulation-induced health hazards. Potentially fatal consequences and limited treatment methods of OP poisoning necessitate the need for the development of reliable, selective, cost-effective, and sensitive methods of OP detection. To tackle this issue, the development of effective devices and methods is required to sensitively detect as well as degrade OPs.

Micropropagation of Tricholepis roylei Hook. F.-a point endemic species of the Western Himalaya.

Background: Tricholepis roylei Hook. f. is a bushy annual shrub of the Asteraceae family and point endemic species of the Western Himalaya.

Cyanide produced with ethylene by ACS and its incomplete detoxification by β-CAS in mango inflorescence leads to malformation.

Malformation of mango inflorescences (MMI) disease causes severe economic losses worldwide. Present research investigates the underlying causes of MMI. Results revealed significantly higher levels of cyanide, a by-product of ethylene biosynthesis, in malformed inflorescences (MI) of mango cultivars.

Supersonic Cold Spraying for Energy and Environmental Applications: One-Step Scalable Coating Technology for Advanced Micro- and Nanotextured Materials.

Supersonic cold spraying is an emerging technique for rapid deposition of films of materials including micrometer-size and sub-micrometer metal particles, nanoscale ceramic particles, clays, polymers, hybrid materials composed of polymers and particulates, reduced graphene oxide (rGO), and metal-organic frameworks. In this method, particles are accelerated to a high velocity and then impact a substrate at near ambient temperature, where dissipation of their kinetic energy produces strong adhesion. Here, recent progress in fundamentals and applications of cold spraying is reviewed.

Enforced lysosomal biogenesis rescues erythromycin- and clindamycin-induced mitochondria-mediated cell death in human cells.

Antibiotics are the front-line treatment against many bacterial infectious diseases in human. The excessive and long-term use of antibiotics in human cause several side effects. It is important to understand the underlying molecular mechanisms of action of antibiotics in the host cell to avoid the side effects due to the prevalent uses.

Fluorescent Biocompatible Platinum-Porphyrin-Doped Polymeric Hybrid Particles for Oxygen and Glucose Biosensing.

Near infrared (NIR) fluorophores like Pt-porphyrin along with analyte specific enzymes require co-encapsulation in biocompatible and biodegradable carriers in order to be transformed into implantable biosensors for efficient and continuous monitoring of analytes in patients. The main objective of this research is to develop natural, biodegradable, biocompatible and a novel co-encapsulated system of Pt-porphyrin encapsulated polymeric nanoparticle and nano-micro hybrid carriers. A sequential emulsification-solvent evaporation and an air driven atomization technique was used for developing above matrices and testing them for fluorescence based oxygen and glucose biosensing.

Ni-core CuO-shell fibers produced by electrospinning and electroplating as efficient photocathode materials for solar water splitting.

Charge recombination in CuO photocathodes inhibits efficient electron flow and limits the photo-electrochemical performance of these cathodes for solar water splitting. To circumvent this shortcoming, we introduce highly conductive Ni/CuO core-shell structured fibers. The photocurrent density (PCD) achieved with these core-shell fibers exceeded that of fibers without a Ni core by a factor of 2.

Flexible, Freestanding, and Binder-free SnO(x)-ZnO/Carbon Nanofiber Composites for Lithium Ion Battery Anodes.

Here, we demonstrate the production of electrospun SnO(x)-ZnO polyacrylonitrile (PAN) nanofibers (NFs) that are flexible, freestanding, and binder-free. This NF fabric is flexible and thus can be readily tailored into a coin for further cell fabrication. These properties allow volume expansion of the oxide materials and provide shortened diffusion pathways for Li ions than those achieved using the nanoparticle approach.

Enhanced Photoelectrochemical Solar Water Splitting Using a Platinum-Decorated CIGS/CdS/ZnO Photocathode.

A Cu(InGa)Se2 film was modified with CdS/ZnO for application to solar water splitting. Platinum was electrodeposited on the ZnO layer as a hydrogen evolution catalyst. The effects of the electroplating time and acidity level of the electrolyte on the photocurrent density were studied.

Chemical-Bath-Deposited Indium Oxide Microcubes for Solar Water Splitting.

We fabricated films of cubic indium oxide (In2O3) by chemical bath deposition (CBD) for solar water splitting. The fabricated films were characterized by X-ray diffraction analysis, Raman scattering, X-ray photoelectron spectroscopy, and scanning electron microscopy, and the three-dimensional microstructure of the In2O3 cubes was elucidated. The CBD deposition time was varied, to study its effect on the growth of the In2O3 microcubes.

A comparison of hand wrist bone analysis with two different cervical vertebral analysis in measuring skeletal maturation.

Background: Skeletal maturation is an integral part of individual pattern of growth and development and is a continuous process. Peak growth velocity in standing height is the most valid representation of the rate of overall skeletal growth. Ossification changes of hand wrist and cervical vertebrae are the reliable indicators of growth status of individual.

Highly efficient wettability control via three-dimensional (3D) suspension of titania nanoparticles in polystyrene nanofibers.

Electrospinning is a simple and highly versatile method for the large-scale fabrication of polymeric nanofibers. Additives or fillers can also be used to functionalize the nanofibers for use in specific applications. Herein, we demonstrate a novel and efficient way to fabricate superhydrophobic to hydrophilic tunable mats with the combined use of electrospinning and electrospraying that may be suitable for mass production on the merits of rapid deposition.