Publications by authors named "Bhatia Pradeep"

Nosocomial bloodstream infections with multidrug-resistant microorganisms have become a common health threat in intensive care settings worldwide. Understanding antimicrobial resistance and the outcomes of these infections is crucial for addressing this issue. This study aimed to investigate the burden, antimicrobial resistance, and 28-day outcomes of nosocomial bloodstream infections in the intensive care unit.

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  • The study investigated the effectiveness of measuring collapsibility index (CI) of the subclavian vein (SCV) versus the inferior vena cava (IVC) in predicting hypotension after general anesthesia induction in 132 adult patients.
  • During quiet breathing, the SCV-CI and IVC-CI had similar sensitivities and specificities, with SCV-CI showing a sensitivity of 68% and IVC-CI showing 70% for predicting postinduction hypotension.
  • The findings suggest both measurement methods are moderately accurate, with a significant positive correlation between SCV-CI and IVC-CI, especially during quiet breathing.
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  • The study investigates the effects of adding dexmedetomidine as premedication to ketofol for sedation in children undergoing MRI, aiming to improve sedation quality and reduce movement artifacts during scans.
  • A total of 132 children aged 6 months to 10 years were divided into two groups: one receiving dexmedetomidine and ketofol (DK group) and the other receiving only ketofol (K group). Results showed that the DK group had significantly better sedation quality and scan quality, along with lower propofol dosage.
  • The conclusion indicates that administering dexmedetomidine prior to induction enhances sedation quality, reduces the need for additional propofol, and maintains
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Background And Aims: None of the clinical difficult airway predictors are 100% sensitive and specific. Ultrasound is being used for airway assessment, but there is still no established parameters or model to predict difficult laryngoscopy. This observational study was planned to determine the predictive ability of clinical and sonography-based airway assessment parameters for difficult laryngoscopy and intubation.

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Background And Aims: Preoperative parental anxiety can have a profound impact on their children undergoing surgery. The present study was done to analyse the correlation between preoperative parental anxiety and their child's anxiety in paediatric patients undergoing elective surgery.

Methods: Paediatric patients aged 2-12 years, scheduled for elective surgeries under general anaesthesia, were included in the study.

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Background: We compared the modified ROX index and ROX index scores in earlier predictions of high-flow nasal oxygen (HFNO) therapy outcomes in patients with acute respiratory failure.

Methods: We conducted a prospective observational study on 151 acute respiratory failure patients initiated on HFNO therapy. The primary objective of this research was to compare the modified ROX index and ROX index to investigate which score predicted HFNO treatment outcome earlier.

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  • * A total of 103 adult patients with CRAB-related VAP were analyzed, comparing outcomes between those treated with dual and triple antibiotic combinations involving sulbactam.
  • * Results indicate that the triple therapy (sulbactam, polymyxin B, and minocycline) significantly reduced 28-day mortality and improved other health markers compared to the dual therapy, suggesting it may be a more effective treatment option.
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  • The study investigates how levels of micronutrients like calcium, phosphorus, magnesium, and alkaline phosphatase (ALP) are connected to the severity and mortality of COVID-19 in 200 participants (100 patients and 100 controls).
  • It finds that lower levels of calcium, phosphorus, magnesium, and higher levels of ALP are linked to worse outcomes in COVID-19 cases, with specific metrics suggesting these micronutrients influence disease severity.
  • The research highlights the potential for optimizing nutrient levels as a therapeutic approach for COVID-19, while calling for more detailed studies to understand these nutrient interactions better.
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  • The study investigates the prevalence and impact of candidaemia in 67 ICUs across India, assessing how the COVID-19 pandemic influenced its rates and mortality.* -
  • Data from 401,601 patient days revealed higher candidaemia rates in COVID-19 ICUs (2.52/1000 patient days) compared to non-COVID-19 ICUs (1.05/1000 patient days), with associated mortality significantly higher in COVID-19 cases (61% vs. 41%).* -
  • Analysis identified C. tropicalis as the most common isolated species (26.7%), while C. auris, which had a high mortality rate, accounted for 17.5% of isolates
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Background: Patients with coronavirus disease 2019 (COVID-19) infection frequently have hypertension as a co-morbidity, which is linked to adverse outcomes. Antihypertensives may affect the outcome of COVID-19 infection.

Aim: To assess the effects of antihypertensive agents on the outcomes of COVID-19 infection.

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Background: No research has been conducted to compare long-axis in-plane and short-axis out-of-plane techniques for ultrasound-guided posterior tibial artery cannulation in adults. This study compared these two procedures for cannulating the posterior tibial artery.

Methods: This prospective randomized trial included 236 adult patients undergoing general anesthesia who required arterial cannulation.

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Background: Ventilator-associated pneumonia (VAP) is a major cause of morbidity and mortality in patients receiving mechanical ventilation in India. Surveillance of VAP is essential to implement data-based preventive measures. Implementation of ventilator-associated events (VAE) criteria for surveillance has major constraints for low resource settings, which can lead to significant underreporting.

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  • The authors respond to a discussion on various methods of oxygen delivery for post-operative patients experiencing hypoxemia, emphasizing the limitations of traditional nasal prongs.
  • They advocate for a broader exploration of alternative oxygen delivery systems that may offer improved outcomes in critical care settings.
  • The article highlights the importance of individualized patient care and the need for evidence-based practices in managing post-operative hypoxemia effectively.
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Background And Aims: To compare ultra-sonographic dimensions of acoustic target window of the spine in the participants at four different sitting positions namely cross leg sitting (CLP), hamstring stretch (HSP), classical sitting (CSP) and riders sitting position (RSP). The primary objective of this study was to measure the neuraxial acoustic target window (defined as interlaminar distance between L3-L4 lamina). The secondary objective was to compare ultra-sonographic measurements of the depth of ligamentum flavum from the skin, and to compare the diameter of intrathecal space and comfort score in the four different sitting positions.

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  • * Fifty students were divided into two groups, with one group trained on a blue phantom and the other on a human cadaver, after which their skills were evaluated during a practical block performance on patients.
  • * Results showed that students trained on cadavers had faster block performance times and better overall outcomes, including image quality and fewer errors, proving cadaver training is superior for teaching ultrasound-guided regional anesthesia.
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Background And Aims: Modified radical mastectomy (MRM) is associated with moderate severity of postoperative pain. Besides intravenous (IV) analgesics, various nerve blocks are being described for pain relief of MRM patients. We compared erector spinae plane (ESP) block with midpoint transverse process to pleura (MTP) block in these patients for postoperative analgesia.

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Objectives: To investigate the genomic differences between two extensively drug resistant, ST16 strains of Klebsiella pneumoniae recovered from patients in the same ICU, one of which was colistin resistant.

Methods: Antimicrobial susceptibilities of the isolates were determined using VITEK-2. Hybrid assemblies for both strains were generated using Oxford Nanopore and Illumina technologies.

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Background: With the provision of a small positive end-expiratory pressure (PEEP) effect, high-flow nasal oxygen (HFNO) therapy carries a risk of stomach distension. The present study was conducted to find out the air leak in the gastric antrum leading to gastric distension in adult patients with acute respiratory failure receiving HFNO therapy.

Materials And Methods: Adult patients with early hypoxemic respiratory failure requiring HFNO therapy were enrolled in this trial.

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