Primary Leiomyosarcoma of the Thyroid Gland - A Rare Malignancy.

Primary leiomyosarcoma (LMS) of thyroid is rare malignant neoplasm usually seen in elderly patients. These tumours are characterised by a rapidly growing mass in the neck, difficult to diagnose preoperatively and are highly aggressive with high recurrence rates in spite of radical surgery, chemotherapy and radiotherapy. We herein report a case of 50-year-old female with a rapidly growing painless mass in the neck.

9,9-Dimethoxy-7,11-diphenyl-2,4-diazaspiro[5.5]undecane-1,3,5-trione monohydrate.

Due to steric repulsions, the cyclohexane ring in the title compound, C(23)H(24)N(2)O(5).H(2)O, shows some bond-length abnormalities and adopts a chair conformation. The pyrimidine and cyclohexane rings are approximately perpendicular to each other, and the phenyl rings are equatorial.

Degradation of chlorophenoxyacetic acids by the lignin-degrading fungus .

We have examined the degradation of C ring- and side-chain-labelled 2,4,5-trichlorophenoxyacetic acid by and The effects of Mn on the degradation of these radiolabeled substrates by D. squalens and the effect of nitrogen limitation on their degradation by suggested that in both fungi, side-chain cleavage was catalysed by a mechanism independent of the lignin degradation system, whereas the degradation of the aromatic ring was dependent on the lignin degradative system. Using unlabelled substrates, a pathway for the degradation of chlorophenoxyacetic acids was elucidated in Time courses for the degradation of unlabelled chlorophenoxyacetic acids by demonstrated that the corresponding chlorophenol was the initial product formed.