Utility of various functional and anatomic imaging modalities for detection of ectopic adrenocorticotropin-secreting tumors.

Context: Because ectopic ACTH-secreting (EAS) tumors are often occult, improved imaging is needed.

Objective: Our objective was to evaluate the utility of [(111)In-DTPA-d-Phe]pentetreotide scintigraphy [octreotide (OCT)] imaging at 6 mCi [low OCT (LOCT)] and 18 mCi [high OCT (HOCT)], [(18)F]fluorodeoxyglucose (FDG)-positron emission tomography (PET) and [(18)F]l-3,4-dihydroxyphenylalanine (F-DOPA)-PET scans, computed tomography (CT), and magnetic resonance imaging (MRI).

Design And Setting: The study was a prospective evaluation at a clinical research center.