Publications by authors named "Bharati Dhanluxmi Ratanjee"
Article Synopsis
- High density lipoprotein cholesterol (HDL-C) levels are inversely related to the risk of atherosclerotic cardiovascular disease (ASCVD), but the role of endothelial lipase (EL), which modifies HDL, in this relationship is not well understood.
- The study aimed to investigate whether elevated HDL-C resulting from EL deficiency provides any protective effect against ASCVD by analyzing patients with a specific genetic mutation in the LIPG gene.
- Results showed that despite a higher concentration of HDL-C in patients with LIPG variants, there was no clear association between HDL levels and vascular disease, suggesting that current risk assessment models may not apply to these patients.
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