An observational study of root-cause analysis of medication errors in elderly with methotrexate toxicity.

Introduction: Medication errors are inherent in a healthcare system. This results in both time and cost burdens for both the patient and the health system. The aim of this study was to conduct a root-cause analysis of medication errors in elderly patients with methotrexate toxicity, analyze associated factors, and propose solutions.

Acute Chest Syndrome Masquerading As Sepsis: A Rare Presentation of Sickle Cell Anemia Complication.

Sickle cell disease in adults leads to various complications by hemolytic anemia and vaso-occlusion. Acute chest syndrome (ACS) is a severe life-threatening complication that can lead to multiple organ dysfunction and rapidly progressing respiratory failure. Early recognition and timely management are vital and lifesaving.

Innovative Application of Ziplock Tags for External Tissue Expansion.

Tissue expansion is a technique, which uses the biomechanical properties of skin and thereby aiding in wound closure. Commercially available devices for external expansion are not cost-effective. Hence, in this article, we would like to share our experience of innovative use of ziplock as external tissue expansion.

Innovative Cost-Effective Application of Donut Dressing in Skin Grafting.

One of the measures for the successful take of a skin graft is the prevention of friction, especially in cases of pressure ulcers in patients with head injury leading to altered sensorium. With existing measures such as the use of a pressure-relieving bed, frequent change of position, etc graft loss is common. Some additional measures are required.

Autologous Platelet-rich Plasma Enriched Pixel Grafting.

Autologous platelet-rich plasma contains concentrated platelets after graded centrifugation, which has various applications. Skin grafting is an age-old procedure, which has been used for wound coverage. But the healing process is longer and may be difficult, depending on the wound site, skin defect size, and patient comorbidities, and is difficult to be carried out in patients who have limited donor sites, such as in burns or those who are not fit for long procedures.

Role of Phenytoin in Diabetic Foot Ulcers.

Of the complications of diabetes mellitus, foot ulcers are the most dreaded complications, as they can progress at an alarming rate and can be very difficult to treat. Various modalities have been described in the treatment of diabetic foot ulcers. One such modality of phenytoin therapy uses the disadvantage of the drug, that is, gingival hyperplasia to the advantage of wound healing.

Multi-angle ZnO microstructures grown on Ag nanorods array for plasmon-enhanced near-UV-blue light emitter.

Metal enhanced ultraviolet light emission has been explored in ZnO/Ag hybrid structures prepared by hydrothermal growth of multi-angled ZnO nanorods on slanted Ag nanorods array fabricated by the thermal evaporation technique. Slanted Ag nanorods are realized to be the stacking of non-spherical Ag nanoparticles, resulting in asymmetric surface plasmon resonance spectra. The surface roughness of Ag nanorod array films significantly influences the growth mechanism of ZnO nanorods, leading to the formation of multi-angled ZnO microflowers.

Intrinsic paramagnetic defects probe the superionic phase transition in mechanochemically synthesized AgI nanocrystals.

Electron paramagnetic resonance (EPR) of two intrinsic paramagnetic centers generated by soft mechanochemistry of Ag and I to yield zinc blende gamma-AgI nanoparticles (approximately 38 nm) has been used for the first time to probe the gamma-alpha (body centered cubic) superionic phase transitions in AgI at (423 +/- 1) K. These results are agreeable with the differential scanning calorimetric studies. A transmission electron microscope picture shows the average crystallite size in the range of approximately 30-40 nm.

Effect of Sn doping on the growth and optical properties of AgI nanoparticles.

Controlled iodization and Sn doping of vacuum-evaporated Ag films has helped understand the initial-stage kinetics of AgI nanoparticle growth under ambient conditions. Use of XRD, optical spectroscopy, and AFM has unravelled systematic correlation between Sn-induced disorder in Ag crystal structure, nanoparticle size, and exciton growth dynamics. Sn doping of Ag leads to three specific effects: removal of UV absorption minimum in Ag, introduction of a plasmon-type absorption in the red region, and a reduction in particle size in thicker (than 10 nm) films (but an increase in particle size in 10 nm films) relative to that in undoped Ag films.