The changing landscape of small cell lung cancer.

Background: Small-cell lung cancer (SCLC) is characterized by rapid proliferation and early dissemination. The objective of this study was to examine the demographic trends and outcomes in SCLC.

Methods: The authors queried the National Cancer Institute's Surveillance, Epidemiology, and End Results database to assess the trends in incidence, demographics, staging, and survival for SCLC from 1975 to 2019.

OpenStreetMap data for alcohol research: Reliability assessment and quality indicators.

There is a growing interest in using OpenStreetMap [OSM] data in health research. We evaluate the usefulness of OSM data for researching the spatial availability of alcohol, a field which has been hampered by data access difficulties. We find OSM data is about 50% complete, which appears adequate for replicating findings from other studies using alcohol licensing data.

New insights into the molecular profile of lung adenocarcinoma and implications for therapy.

Lung cancer is a molecularly heterogeneous disease. The advent of next-generation sequencing techniques has significantly advanced our understanding of the complex molecular underpinnings of lung cancer. Furthermore, the development of targeted therapies has significantly altered the landscape of lung cancer therapy over the past decade.