Pseudophilautus regius is a bush frog originally described from the dry zones of Sri Lanka. In the present study, P. regius is being reported from the Eastern Ghats of Andhra Pradesh, India as a new record for the country.
View Article and Find Full Text PDFWith the recent COVID-19 pandemic, wearing masks has become a necessity in our daily lives. People are encouraged to wear masks to protect themselves from the outside world and thus from infection with COVID-19. The presence of masks raised serious concerns about the accuracy of existing facial recognition systems since most of the facial features are obscured by the mask.
View Article and Find Full Text PDFBackground: Neurofibromatosis type 1 is an inherited cancer predisposition syndrome that is caused by a mutation in the NF1 gene that encodes neurofibromin. Patients with neurofibromatosis type 1 have a higher risk of gastrointestinal stromal tumor. This study reports the case of a patient with gastrointestinal stromal tumor who was later diagnosed to have neurofibromatosis type 1 and, unlike usual features, had some uncommon features such as occurrence at an early age and unusual site of origin.
View Article and Find Full Text PDFBackground: In the absence of a specific drug for COVID 19, treatment with plant extracts could be an option worthy of further investigation and has motivated to evaluate the safety and anti-SARS-CoV-2 activity of plant extracts.
Purpose: To screen the phytochemicals for anti-SARS-CoV-2 and evaluate their safety and efficacy and
Method: The phytochemicals for anti-SARS-CoV-2 were screened using molecular docking. The hits generated from screening were subjected for extraction, isolation and purification.
Aim And Objectives: Phytophthora infestans (Mont.) de Bary, the fungal pathogen causes late blight, which results in devastating economic loss among the Solanaceae. The bacillus lipopeptides show the antagonistic activity against the many plant pathogens, among bacillus lipopeptides reported as the antifungal gene.
View Article and Find Full Text PDFAlthough various advancements in radical surgery and neoadjuvant chemotherapy have been developed in treating osteosarcoma (OS), their clinical prognosis remains poor. A synthetic chemical compound, 3-hydroxylflavone, that is reported to regulate ROS production is known to inhibit human bone osteosarcoma cells. However, its role and mechanism in human OS cells remains unclear.
View Article and Find Full Text PDFObjective: The current study reports a green, rapid and one-pot synthesis of FeSO4 nanoparticles using Hibiscus rosasinensis floral extract as a reducing and capping agent. 0.5M of FeSO4 was stirred with the floral extract of H.
View Article and Find Full Text PDFJ Assoc Physicians India
December 2017
Splenic abscesses caused by Salmonella typhi are a very rare complication of typhoid fever in this era of use of specific antibiotics. Co-infection with Leptospira in such a patient is even rarer. Clinical diagnosis of splenic abscess caused by Salmonella is difficult owing to its rarity, being insidious in onset and having nonspecific clinical presentation.
View Article and Find Full Text PDFDuring metastasis, cancer cells transcend from primary site to normal cells area upon attaining epithelial to mesenchymal transition (EMT) causing malignant cancer disease. Increased expression of TGF-β and its receptor ALK5 is an important hallmark of malignant cancer. In the present study, efficacy of curcumin and its analogues as inhibitors of ALK5 (TGFβR-I) receptor was evaluated using in silico approaches.
View Article and Find Full Text PDF, commonly known as job's tear, is a tall grain-bearing tropical plant of the family . The ethanolic root extract (ERE) of the plant was investigated for the first time for anti-venom activity against Indian cobra venom. studies were conducted to determine neutralization of phospholipase A (PLA) activity of the venom by the ERE.
View Article and Find Full Text PDFTo investigate the effectiveness, efficiency and cost gains in collecting patient eye health information from remote rural villages of India by trained field investigators through an Android Based Tablet Application namely 'Sankara Electronic Remote Vision Information System (SERVIS)". During January and March 2016, a population based cross-sectional study was conducted in three Indian states employing SERVIS and manual method. The SERVIS application has a 48-items survey instrument programed into the application.
View Article and Find Full Text PDFACS Appl Mater Interfaces
January 2017
Ultrathin epitaxial films (10-90 nm thick) of VO have been grown on c-AlO by atomic layer deposition using vanadyl acetylacetonate as the vanadium precursor along with oxygen plasma. Various process parameters have been optimized for the purpose, and excellent crystalline films could be obtained below 200 °C, without the need for post-heat treatment. With a moderate temperature window, the process yields a growth rate of 0.
View Article and Find Full Text PDFEur J Med Chem
August 2010
A new series of 2-substituted 4-(2,5-dichloro thienyl)-1,3-thiazoles are synthesized by the reaction of 2-bromo-1-(2,5-dichlorothien-3-yl) ethanone with thiourea and substituted thioamides. The newly synthesized compounds 4a-e are characterized by analytical (1)H NMR, (13)C NMR and mass spectral data. The newly synthesized compounds are screened for antifungal and antibacterial activities.
View Article and Find Full Text PDF