A prospective study to evaluate the role of duodenal bulb biopsy in the diagnosis of celiac disease.

Background: Celiac disease (CeD) requires a biopsy from the small intestine to confirm the diagnosis. Conventionally, duodenal bulb (D1) was avoided as a biopsy site due to histological confounding factors at this site. However, sometimes, the bulb mucosa is the only affected site.