Publications by authors named "Bhadrish Vallabh"
Article Synopsis
- The discussion around anesthetics' environmental impacts has mainly centered on greenhouse gas (GHG) emissions from inhaled agents, with increasing interest in total intravenous anesthesia (TIVA), particularly propofol.
- Researchers propose expanding the study of general anesthetics to include life cycle assessment (LCA), which evaluates the overall environmental effects throughout the anesthetic's life stages, including manufacturing and disposal.
- Initial LCA studies show that sevoflurane has a lower carbon footprint than TIVA, but they usually overlook other environmental concerns like waste toxicity and lack comprehensive GHG emissions data related to TIVA components, indicating the need for further research while prioritizing patient care in current practices.
Background: Lopinavir/ritonavir (LPV/r-A, Kaletra®), a fixed dose, co-formulated antiviral therapy for the treatment of HIV infection has been used worldwide for over two decades. Both active substances have low solubility in water and low membrane permeability. LPV/r-A tablets contain key excipients critical to ensuring acceptable bioavailability of lopinavir and ritonavir in humans.
View Article and Find Full Text PDFIntroduction: This analysis explored laboratory mineral and bone disorder parameters and management of secondary hyperparathyroidism in patients undergoing hemodialysis in Belgium, Canada, China, France, Germany, Italy, Japan, Russia, Saudi Arabia, Spain, Sweden, the UK, and the USA.
Methods: Analyses used demographic, medication, and laboratory data collected in the prospective Dialysis Outcomes and Practice Patterns Study (2012-2015). The analysis included 20,612 patients in 543 facilities.