Publications by authors named "Bhaben Sharmah"
Glucose-dependent insulin delivery systems have been recognized as a promising approach for controlling blood sugar levels in individuals with diabetes mellitus (DM). Recently, titanium dioxide nanoparticles have garnered huge attention in scientific research for their small size and effective drug delivery capabilities. In this study, we developed alizarin (AL)-capped phenylboronic acid (PBA)-functionalized titanium dioxide nanoparticles (TiO) for glucose-sensitive insulin delivery (TiO-PBA-INS-AL) aiming to manage both blood sugar levels and its associated organ pathology in DM.
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- Nanoceria (NC) is being explored for its effectiveness in drug delivery and reducing oxidative stress, particularly in diabetes treatment.
- The researchers created a dextran-capped insulin nanoparticle (NC-PBA-INS-Dex) that responds to glucose levels, facilitating insulin delivery and combating oxidative stress in diabetic conditions.
- The study showed that NC-PBA-INS-Dex enhances insulin delivery and effectiveness, maintaining stable blood sugar levels for longer periods and exhibiting potential for both oral and systemic administration in diabetic animals.
The present study aims to investigate the anti-inflammatory potential of the leaf hydroalcoholic extract of Piper betleoides C. DC., also known as "Jangli Paan" in Northeast India, using lipopolysaccharide (LPS)-treated both cell culture (RAW264.
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