Natural cosmetic products have recently re-emerged as a novel tool able to counteract skin aging and skin related damages. In addition, recently achieved progress in nanomedicine opens a novel approach yielding from combination of modern nanotechnology with traditional treatment for innovative pharmacotherapeutics. In the present study, we investigated the antiaging effect of a pretreatment with natural extract combined with a polycaprolactone nanofibrous scaffold (NanoPCL-M) on skin cell populations exposed to UV.
View Article and Find Full Text PDFHydrogels are suitable for osteochondral defect regeneration as they mimic the viscoelastic environment of cartilage. However, their biomechanical properties are not sufficient to withstand high mechanical forces. Therefore, we have prepared electrospun poly-ε-caprolactone-chitosan (PCL-chit) and poly(ethylene oxide)-chitosan (PEO-chit) nanofibers, and FTIR analysis confirmed successful blending of chitosan with other polymers.
View Article and Find Full Text PDFThe aim of the study was to evaluate the safety and efficacy of a new therapeutic approach to skin defects resulting from split thickness grafting. Within the study, nanofiber-based dressings fabricated using polyvinyl alcohol (PVA) and poly-ε-caprolactone (PCL) were used, with different mass density. The study was performed in 1 female minipig.
View Article and Find Full Text PDFFor biodegradable porous scaffolds to have a potential application in cartilage regeneration, they should enable cell growth and differentiation and should have adequate mechanical properties. In this study, our aim was to prepare biocompatible scaffolds with improved biomechanical properties. To this end, we have developed foam scaffolds from poly-epsilon-caprolactone (PCL) with incorporated chitosan microparticles.
View Article and Find Full Text PDFActa Chir Orthop Traumatol Cech
October 2012
In the submitted paper the authors describe the principle and technique of implantation of a non-cemented self-expanding socket. On an anatomical model they demonstrate different technical details of implantation and provide a more accurate account of their own surgical technique. They draw attention to the most frequent errors the surgeon may comit.
View Article and Find Full Text PDFIn 1989-1992 the authors used at the Orthopaedic Clinic, First Medical Faculty, Charles University Prague 34 ceramic conical non-cemented sockets. They used 12 original sockets type AUTOPHOR Osteo Co. and 22 local sockets manufactured by Dias Co.
View Article and Find Full Text PDFActa Chir Orthop Traumatol Cech
June 1994
The authors present a variant of Desault's bandage for fixation of conservatively treated injuries of the proximal end of the humerus and for fixation of the upper extremity after surgery in this area. The bandage is made with elastic net bandage (called pruban), it is sufficiently strong and its application is easier and less time consuming.
View Article and Find Full Text PDFActa Chir Orthop Traumatol Cech
November 2015
The authors inform about a new traction frame for the lower extremity to be used by the health service in the Czechoslovak Army. They present fundamental requirements set for the development of this plate and perspectives of its series production. Key words: metal traction frame, lower extremity, immobilization.
View Article and Find Full Text PDF