Publications by authors named "Beye M"

Introduction: Micronutrient deficiencies are common among women of reproductive age (WRA) and children in Senegal. Large-scale food fortification (LSFF) can help fill gaps in dietary intakes.

Methods: We used household food consumption data to model the contributions of existing LSFF programs (vitamin A-fortified refined oil and iron and folic acid-fortified wheat flour) and the potential contributions of expanding these programs to meeting the micronutrient requirements of WRA (15-49 years) and children (6-59 months).

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Introduction: A urethro-rectal fistula is an abnormal communication between the urethra and the rectum. It is a rare entity. It is most often an iatrogenic lesion during prostate surgery.

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The evolutionary changes from solitary to eusocial living in vertebrates and invertebrates are associated with the diversification of social interactions and the development of queen and worker castes. Despite strong innate patterns, our understanding of the mechanisms manifesting these sophisticated behaviors is still rudimentary. Here, we show that () manifests group-supporting behaviors in the honeybee () worker caste.

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Food and condiment fortification programs are needed to address micronutrient deficiencies and their health, developmental, and mortality consequences; but these programs are never free. Knowing program costs and their allocation across stakeholders is essential to design and manage effective, efficient, and sustainable programs. We developed 10-year hypothetical bouillon fortification program cost models for Nigeria, Senegal, and Burkina Faso that included start-up and operational costs for government and industry, as well as premix costs generated by an embedded premix cost calculator to allow for alternative premix formulas in cost calculations.

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Article Synopsis
  • Complementary sex determination in honeybees is influenced by the csd gene, which has different alleles determining whether an individual develops as male or female based on their genotype.
  • Recent research has shed light on how the Csd protein distinguishes between different genetic variants and regulates pathways crucial for sexual differentiation.
  • The study emphasizes the evolutionary implications of these mechanisms and how specific mutations can reveal insights into the development of new regulatory functions in sex determination.
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Providing children healthy diversified diets is important for their optimal growth and development. The high prevalence of under-nourishment during the critical early life period is of serious concern in West Africa. We assessed the level of dietary diversity and associated factors for children aged 6-23 months in Côte d'Ivoire, Niger and Senegal.

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Article Synopsis
  • Senegal mandates that refined oil be fortified with vitamin A and wheat flour with iron and folic acid to combat micronutrient deficiencies, and expanding these efforts to include bouillon could further improve nutrition.
  • Using food consumption data from 2018-2019, the study assessed how fortified bouillon could help meet essential micronutrient needs for women of reproductive age and young children.
  • Results indicate that fortifying bouillon could significantly decrease the prevalence of dietary inadequacy for several key nutrients, with the greatest benefits seen among poorer and rural households.
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Background: COVID-19 remains a global public health challenge due to new immune-evasive SARS-CoV-2 variants and heterogeneous immunity.

Methods: In this cross-sectional study, we evaluated the adaptive immune responses in US active duty personnel who completed a COVID-19 primary vaccine series and had heterogenous SARS-CoV-2 vaccination and infection histories to 3 previously dominant variants (ancestral, Delta, BA.5) and 3 circulating variants (XBB.

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Background: Vitamin A deficiency (VAD) is a leading contributor to the poor health and nutrition of young children in sub-Saharan Africa. Funding constraints are compelling many countries to shift from longstanding campaigns to integrating vitamin A supplementation (VAS) into routine health services. We assessed child VAS coverage and associated factors for integrated delivery systems in Mozambique, Senegal, and Sierra Leone and for a campaign-based delivery strategy in Tanzania.

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The burden of micronutrient malnutrition is high among women of reproductive age (WRA) in sub-Saharan Africa. We examined the dietary quality and associated factors for WRA in Cameroon, Côte d'Ivoire, Kenya, Nigeria, Senegal, and Tanzania. Data were collected from women aged 15-49 years using representative Diet Quality Questionnaire surveys.

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A change of orbital state alters the coupling between ions and their surroundings drastically. Orbital excitations are hence key to understand and control interaction of ions. Rare-earth elements with strong magneto-crystalline anisotropy (MCA) are important ingredients for magnetic devices.

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Article Synopsis
  • The study investigates the genomic variations of SARS-CoV-2 in Mauritania between September and November 2021, filling a gap in understanding the virus's mutations in this region.
  • A total of 54 clinical isolates were sequenced, with the Delta variant being the most common, particularly the sub-lineage AY.34.
  • It highlights the need for better regional sequencing facilities in West Africa to monitor viral mutations and address potential impacts on vaccine effectiveness and disease severity.
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Background: Most low- and middle-income countries do not have a mature prehospital system limiting access to definitive care. This study sought to describe the current state of the prehospital system in Senegal and offer recommendations aimed at improving system capacity and population access to definitive care.

Methods: Structured interviews were conducted with key informants in various regions throughout the country using qualitative and quantitative techniques.

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Objectives: Influenza is frequent among pilgrims participating in the Grand Magal de Touba (GMT), in Senegal, with a potential to spread to contacts when they return home.

Methods: Ill pilgrims consulting at a health care center in Mbacké city close to Touba during the 2021 GMT, pilgrims returning to Dielmo and Ndiop villages, and patients who did not travel to Touba and consulted at health care centers in these two villages in 2021 were tested for the influenza virus by polymerase chain reaction on nasopharyngeal samples. Next-generation sequencing and comparative and phylogenetic analyses of influenza A virus genomes were performed.

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Among oral microbiota methanogens, () has remained less studied than the well-characterised and cultivated methanogens and . has been associated with different oral pathologies and was co-isolated with the bacterium () in one case of severe periodontitis. Here, reporting on two additional necrotic pulp cases yielded the opportunity to characterise two co-cultivated isolates, both with , as non-motile, 1-2-µm-long and 0.

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According to the latest WHO estimates (2015) of the global burden of foodborne diseases, is responsible for one of the most serious foodborne infections and commonly results in severe clinical outcomes. The 2013 French MONALISA prospective cohort identified that women born in Africa has a 3-fold increase in the risk of maternal neonatal listeriosis. One of the largest outbreaks occurred in South Africa in 2017-2018 with over 1,000 cases.

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Free-electron lasers provide bright, ultrashort, and monochromatic x-ray pulses, enabling novel spectroscopic measurements not only with femtosecond temporal resolution: The high fluence of their x-ray pulses can also easily enter the regime of the non-linear x-ray-matter interaction. Entering this regime necessitates a rigorous analysis and reliable prediction of the relevant non-linear processes for future experiment designs. Here, we show non-linear changes in the -edge absorption of metallic nickel thin films, measured with fluences up to 60 J/cm.

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The on-going emergence of the Omicron BA.2.86 variant is one of the major events in SARS-CoV-2 genetic evolution that remain enigmatic regarding the overall virus mutation rate, together with the emergence of the initial Omicron variant, BA.

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Sex in honeybees, , is genetically determined by heterozygous versus homo/hemizygous genotypes involving numerous alleles at the single complementary sex determination locus. The molecular mechanism of sex determination is however unknown because there are more than 4950 known possible allele combinations, but only two sexes in the species. We show how protein variants expressed from complementary sex determiner () gene determine sex.

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West Africa faced the COVID-19 pandemic in early March 2020 and, as of March 31, 2022, had more than 900,000 confirmed cases and more than 12,000 deaths. During this period, SARS-CoV-2 genomes evolved genetically, resulting in the emergence of distinct lineages. This review was conducted to provide the epidemiological profile of COVID-19, the mutational profile of SARS-CoV-2, and the dynamics of its lineages in the 16 west African countries by analyzing data from 33 studies and seven situation reports.

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Blood is a precious biological liquid that is normally sterile. Therefore, bacteria in the bloodstream are shown a priori anomaly. A blood culture is systematically performed to diagnose the cause of the bacteremia.

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Article Synopsis
  • Researchers used whole genome sequencing to study SARS-CoV-2 mutations in urban Senegal during the peak COVID-19 wave from March to April 2021.
  • They sequenced 291 nasopharyngeal samples, revealing 16 distinct genomic lineages, with B.1.1.420 being the most prevalent despite the presence of the Alpha variant.
  • The study identified 1125 SNPs compared to the Wuhan reference genome, with notable diversification showing the emergence of a unique Senegalese strain belonging to the Brazilian Gamma variant lineage.
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The emergence of the Coronavirus Disease 2019 (COVID-19) pandemic has fostered the use of high-throughput techniques to sequence the entire severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) genome and track its evolution. The present study proposes a rapid and relatively less expensive sequencing protocol for 384 samples by adapting the use of an Illumina NovaSeq library to an Illumina MiSeq flow cell instrument. The SARS-CoV-2 genome sequences obtained with Illumina NovaSeq and those obtained using MiSeq instruments were compared with the objective to validate the new, modified protocol.

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Femtosecond transient soft X-ray absorption spectroscopy (XAS) is a very promising technique that can be employed at X-ray free-electron lasers (FELs) to investigate out-of-equilibrium dynamics for material and energy research. Here, a dedicated setup for soft X-rays available at the Spectroscopy and Coherent Scattering (SCS) instrument at the European X-ray Free-Electron Laser (European XFEL) is presented. It consists of a beam-splitting off-axis zone plate (BOZ) used in transmission to create three copies of the incoming beam, which are used to measure the transmitted intensity through the excited and unexcited sample, as well as to monitor the incoming intensity.

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