Publications by authors named "Beverly L Hersh"
Article Synopsis
- The study focused on understanding the high mortality rates (around 20%) associated with periprosthetic joint infections (PJI), aiming to identify whether this was linked to pre-existing health issues, the infection itself, or the treatment received.
- In a multicenter study, 184 patients undergoing septic revision total knee arthroplasty (TKA) were compared with 38 patients receiving aseptic revision TKA, revealing that the septic group had a higher early mortality rate at various time points post-surgery.
- Although both groups showed increased health complications over time, the septic group had higher preoperative comorbidity scores, suggesting that mortality in septic TKA is related to overall frailty
Background: Diagnosis and treatment of culture negative total knee arthroplasty (TKA) periprosthetic joint infection (PJI) is challenging. There is debate over whether culture negative PJI confers increased risk of failure and which organisms are responsible. It is also unclear as to what factors predict conversion from culture negative to culture positivity.
View Article and Find Full Text PDFBackground: Total knee arthroplasty (TKA) periprosthetic joint infection (PJI) can be managed with debridement, antibiotic therapy, and implant retention (DAIR). Oral antibiotics can be used after DAIR for an extended time period to improve outcomes. The objective of this study was to compare DAIR failure rates and adverse events between an initial course of intravenous antibiotic therapy and the addition of extended treatment with oral antibiotics.
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