Objective: maternal mortality represents the single greatest health disparity between high and low income countries. This inequity is especially felt in low income countries in sub Saharan Africa and Southeast Asia where 99% of the global burden of maternal death is borne. A goal of MDG 5 is to reduce maternal mortality and have a skilled attendant at every birth by 2015.
View Article and Find Full Text PDFObjectives: To further validate the safety and diagnostic accuracy of percutaneous core biopsy in small renal masses ([SRMs]≤4 cm) in response to the rising prevalence of renal 'incidentalomas'. To determine the value of percutaneous core biopsy in its ability to influence the choice of intervention or surveillance for the management of SRMs.
Patients And Methods: We collected data on the incidence of benign, malignant and non-diagnostic samples from 268 SRM (clinical T1a) biopsies performed at our institution between 1998 and 2009.
Purpose: We designed and fully evaluated the performance of a nomogram to identify patients with prostate cancer who may be suitable for active surveillance.
Materials And Methods: We developed a nomogram to predict the probability of minimal prostate cancer (total tumor volume less than 0.5 cc, organ confined disease and no Gleason pattern 4 or 5) using preoperative data on 2,525 Australian patients who underwent radical prostatectomy.
Various patterns of high-grade prostatic intraepithelial neoplasia have been have been described, many of which show morphologic similarity to patterns of prostatic intraductal carcinoma, which is thought to develop either directly from high-grade prostatic intraepithelial neoplasia or by invasion of existing ducts by Gleason pattern 4 or 5 carcinoma. We document a rare and previously unreported "desquamating apoptotic variant" of high-grade prostatic intraepithelial neoplasia where desquamating cells containing apoptotic nuclear material coalesce in the gland lumens to form basophilic intraluminal masses in up to one third of involved acini. This lesion shares features of both high-grade prostatic intraepithelial neoplasia and prostatic intraductal carcinoma and supports the hypothesis that some forms of prostatic intraductal carcinoma evolve directly from high-grade prostatic intraepithelial neoplasia.
View Article and Find Full Text PDFObjective: To evaluate new variables in prostate pathology reporting including, the per cent of Gleason patterns 4 and/or 5 (% 4/5), presence or absence of intraductal carcinoma of the prostate (IDCP), tumour volume and the prostatic zone of tumour origin as predictors of post-radical-prostatectomy (RP) biochemical recurrence (BCR). To develop an optimal postoperative nomogram for patients with prostate cancer.
Patients And Methods: Our study cohort was 1939 eligible patients from the Abbott West Australian Prostatectomy Database.
Purpose: Attitudes and beliefs of First Nation Cree women living in a reserve community were explored to gain insights into how cervical screening could be better utilized.
Method: Focused ethnography utilizing participant observation and interviews ( n = 8) with participants having experience with cervical screening and/or cancer was conducted.
Results: Women did not believe they had adequate information and were resistant to screening because of embarrassment caused by the procedure and fear of cancer, which was viewed as a "death sentence.
Childbirth is a significant event in the lives of women and their families. It is a critical time in the human development that transforms women into mothers. Women remember their childbirth for the rest of their lives.
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