Publications by authors named "Beuren A"

Article Synopsis
  • Nutrition significantly impacts cancer care by supporting patients through treatment and recovery phases.
  • Malnutrition and muscle loss from cancer and its treatments can worsen symptoms and delay recovery, making nutritional support essential.
  • Personalized dietary recommendations, guided by registered dietitians, are crucial for optimizing health outcomes and enhancing the quality of life for cancer patients and survivors.
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Purpose: To identify the effects of prophylactic, non-pharmacological measures on the progression of dysphagia in patients with head and neck cancer undergoing radiotherapy.

Research Strategies: The search was performed in Medline (via PubMed), Scopus, and Embase databases, as well as in the gray literature.

Selection Criteria: Randomized clinical trials were included, with adult patients (≥ 18 years old) and diagnosed with head and neck cancer, treated with radiotherapy (with or without surgery and chemotherapy), and submitted to non-pharmacological protocols for the prevention of dysphagia.

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Article Synopsis
  • The study evaluated the effectiveness of cervical ultrasonography and parathyroid scintigraphy in locating abnormal parathyroid glands in patients with primary hyperparathyroidism (PHPT) before surgery.
  • Ultrasonography was found to detect enlarged glands in 87% of patients and had a higher accuracy in predicting surgical findings compared to scintigraphy, which detected them in 79% of cases.
  • The researchers concluded that cervical ultrasonography should be the preferred tool for preoperative localization of affected glands in PHPT due to its better predictive value, especially for solitary adenomas.
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Aortoventriculoplasty (AVP) is an established operative procedure for the enlargement of different types of severe left ventricular outflow tract obstruction. Between 1974 and 1985 75 aortoventriculoplasties were carried out in 72 patients ranging from 5 to 34 years of age. Three patients had to be reoperated upon due to significant right ventricular outflow tract obstruction, outgrown prosthesis, and dissecting aortic aneurysm.

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Forty two children and two young adults who were long term survivors of either intracardiac or extracardiac valve replacement with glutaraldehyde porcine valves form the basis of this report. The follow-up period varied from 6 months to 9 years. Ten of eleven intracardiac valves developed some dysfunction--the eleventh patient died from other causes.

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The preoperative and postoperative findings in 627 patients operated for correction of tetralogy of Fallot (TOF) in the period 1960 to 1984 were analyzed in order to evaluate the clinical and hemodynamic late results. The average age was 7.2 years (range 9 months to 30 years).

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The value of cross-sectional sector echocardiography in the visualization of discrete subaortic stenosis (DSS) was investigated using an 80 degrees phased-array sector scanner with simultaneously derived M-mode outputs. Thirty-three patients (including 22 postoperative patients) with proven DSS were investigated and divided into two groups: group I--discrete membranous type; and group II--diffuse fibromuscular type. In group I (15 patients), two isolated subaortic ridges were identified as discrete linear echoes in the long axis of the outflow tract in five patients.

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Cross-sectional and concurrent M-mode echocardiograms of the left ventricular outflow tract and the ascending aorta were performed in 80 patients with supravalvar aortic stenosis (SVAS) selected from a total of 178 patients in whom the diagnosis had been established earlier by cardiac catheterization and angiocardiography. Visualization of the area of obstruction was possible in 77 patients using the cross-sectional system. In 34 cases recatheterization and angiocardiography of the left heart were carried out.

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Since the first clinical application of aortoventriculoplasty for tunnel subaortic stenosis in 1974 the indication for this method was extended to other types of left ventricular outflow tract stenoses (LVOTO). The operative technique consists of enlarging both the left and right ventricular outflow tracts and inserting an aortic prosthetic valve. 47 operations have been performed in patients with various types of LVOTO: 8 narrow annulus, 23 diffuse subaortic stenosis (multiple level stenosis), 9 complex forms of tunnel subaortic stenosis (Shone complex) 3 outgrown prosthesis, 4 obstructive idiopathic hypertrophic subaortic stenosis.

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Between June 1974 and July 1981, aortoventriculoplasty (AVP) has been applied in 57 patients with several types of left ventricular outflow tract obstruction ranging in age from 5 to 34 years. There were 7 early deaths (mortality 12%); 5 of these occurred in the first 10 patients operated upon. Eighteen patients developed complete right bundle branch block or left anterior hemiblock or both; in another patient a transient complete left bundle branch block occurred postoperatively.

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Twenty-six patients with tricuspid atresia (15), univentricular heart (7), and single ventricle (4) underwent 27 Fontan or modified Fontan procedures between 1975 and 1981. The age of the patients varied between 4 and 26 years. Twenty patients had had a total of 33 palliative operations prior to correction.

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The results are presented of 44 systematic cardiac catheterizations in 35 patients after successful repair of various types of congenital cyanotic heart disease using a conduit. The operations were performed from 1972 to 1981. The patients were followed from 6 months to 9 years, the mean interval between operation and catheterization was 2.

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From 1972 to 1981, 40 valved extracardiac conduits have been implanted to bridge the right ventricular outflow tract (RVOT) in 37 patients for different complex congenital cardiac anomalies. The patients ranged in age from 2 to 23 years (mean 8.5 years).

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Since 1974 the new concept of aortoventriculoplasty (AVP) has been applied clinically in Göttingen. Out of 1,112 patients with various types of congenital aortic stenosis 502 patients have undergone commissurotomy, resection of a subvalvular ring, myotomy and supravalvular patch plasty. Fifty-seven patients were treated by AVP, in only 11 patients was AVP the first procedure, 46 had had one or more previous operations.

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Pulmonary vascular disease and heart failure are the two major problems in complete transposition of the great arteries (TGA) with increased pulmonary flow. Hypertensive pulmonary vascular disease was observed in patients with complete TGA and increased flow (3.6%) as well as in those without increased pulmonary flow (3.

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Three families with the syndrome of hereditary prolonged QT interval affecting 12 members in two or three generations are described. Four patients with sinus bradycardia and frequent syncopal attacks were investigated by Holter-monitoring, His-bundle electrograms and exercise testing. Corrected QT intervals (QTc) were prolonged from 0.

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18 patients with superior vena cava-right pulmonary artery (Glenn) anastomosis and 7 patients with right atrium-pulmonary artery (Fontan) conduit operation were investigated by selective angiography, oximetry and contrast echocardiography. 11 patients with Glenn anastomosis (61.1%) developed a "steal" syndrome in 4 11/12 to 9 7/12 years postoperatively.

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Total correction of underdeveloped right ventricle related to tricuspid hypoplasia has been performed in 6 patients at the department of thoracic and cardiovascular surgery University Göttingen. In 5 patients reconstruction of a four-chamber-four-valved heart could be accomplished. 1 patient with a poor result after Fontan's operation, performed one year previously, showed a significant growth in size of the hypoplastic right ventricle in the postoperative angiogram, but died 14 hours after reoperation.

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From 1974 to 1978, 11 patients underwent a Rastelli correction in transposition of the great arteries with VSD and obstruction to the pulmonary artery. 2 patients died, a mortality of 18%. All patients received a Hancock-conduit.

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Nineteen patients with tricuspid atresia and reduced lung perfusion (valvular-and/or subvalvular pulmonary stenosis, transposition of the great arteries and/or single atrium) were operated in the period 1975--1979. The surgical procedures employed varied according to the additional cardiac defects. The age of the patients was between 2 and 18 years.

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A new therapeutic concept of enlarging the outflow tracts of both ventricles with a patch and inserting an aortic prosthesis has been developed for the treatment of tunnel subaortic stenosis. This operation has been applied clinically since June 1974 on several types of obstruction in the outflow tract of the left ventricle. Twenty-one operations have been performed on 20 patients under the age of 18 years, with an overall mortality of 24% and no late deaths.

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Supravalvular aortic stenosis is either a syndrome combined with typical face characteristics mental retardation and peripheral pulmonary artery stenosis or it occurs as an isolated congenital heart defect. The diagnosis was confirmed in 137 patients by means of catheterization and angiocardiography; 35 pediatric and 10 adult patients were considered to be candidates for corrective surgery because of the severity of their disease. Age varied from 3 to 32 years.

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Results of aortoventriculoplasty (AVP) are reported in 21 patients with various types of left ventricular outflow tract obstruction (LVOTO). The concept of AVP is based on creating a surgical aortoseptal defect which is patched to provide the largest possible outflow tract to the left ventricle. Lesions consisted of isolated diffuse fibromuscular subaortic stenosis in six patients, diffuse subaortic stenosis and associated other cardiovascular anomalies in five, hypoplastic aortic anulus in two, idiopathic hypertrophic subaortic stenosis (IHSS) in two, and stenosis of a previously implanted aortic valvular prosthesis in three patients.

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