Astrocyte HIF-2α supports learning in a passive avoidance paradigm under hypoxic stress.

Background: The brain is extensively vascularized, useŝ20% of the body's oxygen, and is highly sensitive to changes in oxygen. While synaptic plasticity and memory are impaired in healthy individuals by exposure to mild hypoxia, aged individuals appear to be even more sensitive. Aging is associated with progressive failure in pulmonary and cardiovascular systems, exposing the aged to both chronic and superimposed acute hypoxia.

Outcomes for aging adults following total hip arthroplasty in an acute rehabilitation facility versus a subacute rehabilitation facility: a pilot study.

Purpose: The purpose of our study was to determine if aging adults who received rehabilitation following total hip arthroplasty (THA) due to osteoarthritis had better short-term outcomes in an Inpatient Rehabilitation Facility (IRF) compared with those currently receiving rehabilitation in subacute rehabilitation units.

Methods: Thirty-six adults, aged 65 to 88 years, who received inpatient rehabilitation following THA secondary to osteoarthritis participated in this study. A prospective descriptive study of 4 aging adults receiving rehabilitation in 2 subacute rehabilitation facilities and a retrospective descriptive study of 32 aging adults who received rehabilitation in an IRF were conducted.