Publications by authors named "Betina M Beltrame"
Two morphotypes versus two chemotypes of Psidium cattleyanum: Chemical and pharmacological comparison and a rational approach for marker selection.
J Chromatogr B Analyt Technol Biomed Life Sci
May 2022
Psidium cattleyanum has two morphotypes: one with yellow fruits and other with red fruits. The leaves are popularly used as anti-inflammatory. However, no distinction is made between the types.
View Article and Find Full Text PDFThe present study investigates the chemical composition, anti-inflammatory, and antihypertensive activities, in vitro, from extracts of Cuphea lindmaniana and Cuphea urbaniana leaves. The extraction was performed ultrasound-assisted, and UHPLC/MS analysis was in positive mode ionization. The anti-inflammatory activity of the extracts and miquelianin were assayed at concentrations 0.
View Article and Find Full Text PDFObjective: To determine the incidence of nephropathy induced by intravenous contrast in hospitalized patients undergoing computed tomography (CT).
Materials And Methods: This was a retrospective cohort study involving 1,238 patients who underwent CT with or without intravenous administration of a contrast agent (iopromide). The primary outcome measure was acute kidney injury (AKI), as defined by the traditional criteria-an absolute or relative increase in serum creatinine (SCr) ≥ 0.
The Myrtaceae family is considered one of the largest known botanical families and the genus Psidium is among the most economically interesting. Psidium genus comprises approximately 112 species, and it has been extensively studied, mainly because of Psidium guavaja species. Phytochemical investigations confirmed the presence of phenolics as the main compounds, as well as the essential oils, which were also widely investigated.
View Article and Find Full Text PDFgenus (Lythraceae) popularly known in Brazil as "", it's described as antimicrobial, anti-inflammatory, diuretic and antihypertensive mainly. Investigating the chemotactic ability plays an important role in the identification of new anti-inflammatory agents. Thus, this research aims to assay the antichemotactic activity of hydroethanolic extracts of , , , and as well as the compounds miquelianin and myricitrin.
View Article and Find Full Text PDFArticle Synopsis
- - The study aimed to analyze how effective daptomycin is against vancomycin-resistant Enterococcus faecium bacteraemia, using computer modeling techniques, particularly PK/PD modeling and Monte Carlo simulations.
- - Researchers evaluated the drug's effectiveness through time-kill curves and found significant reductions in bacterial counts with daptomycin doses between 6-10 mg/kg over 18 days, especially in individuals with better kidney function (creatinine clearance of 15-100 mL/min).
- - The findings indicate that while higher doses of daptomycin lead to better therapeutic responses, administering it every 48 hours is not enough to effectively treat the infection, suggesting a need for more frequent dosing.