Publications by authors named "Bethany Sander"
Article Synopsis
- The study explored how psychosocial factors and hormonal changes affect sleep difficulties during menopause, highlighting that sleep issues can lead to physical and mental health problems.
- Researchers involved 101 perimenopausal participants who completed weekly assessments of sleep quality, mood, and hormonal levels over 12 weeks, along with a 24-hour evaluation of hot flashes.
- Findings indicated that prior depression, anxiety, and severe hot flashes worsened sleep, while poor sleep was linked to lower attention and was influenced by stress events and trauma history.
Background: Approximately one in six couples are currently infertile, defined as unable to achieve pregnancy despite 12 or more months of active attempts to conceive. Experiencing infertility has been disproportionately associated with an array of psychological difficulties, particularly in women. However, currently available psychological interventions have had minimal benefits for distress, anxiety, or depression related to infertility.
View Article and Find Full Text PDFPurpose Of Review: This review considers how reproductive aging may impact the trajectory of menstrually related mood disorders (MRMDs) such as premenstrual dysphoric disorder and considers how the treatment of MRMDs might require adjustment as patients approach midlife.
Recent Findings: The early menopause transition is accompanied by important hormonal changes that may exacerbate existing MRMDs. Indeed, recent research confirms that an important subset of women experiences depressive mood in response to perimenopausal elevations in ovarian hormones.
The role of estradiol fluctuation in the pathophysiology of perimenopausal depression: A hypothesis paper.
Psychoneuroendocrinology
November 2021
The menopause transition, which constitutes the five or so years surrounding the final menstrual period, has been established as a time of increased risk for depressive symptoms. While mounting research suggests that exposure to more extreme and fluctuating levels of estradiol (E2) plays a role, it remains unclear which specific trigger is most strongly implicated in the development of depressive mood: acute E2 withdrawal or extreme increases in E2. The current review summarises the literature supporting the role of each, considering research pertaining to perimenopausal depression as well as other reproductive mood disorders in which ovarian hormone change is believed to play a key role, namely premenstrual dysphoric disorder and postpartum depression.
View Article and Find Full Text PDFBackground: The menopause transition is associated with an increased risk of depression. While the mechanisms behind this increased risk are not well understood, the changing perimenopausal hormonal environment has been hypothesized to play a role. The current study examined the potential influence of testosterone and the ratio of testosterone to estradiol as a potential contributor to depressed mood in the menopause transition.
View Article and Find Full Text PDFBackground: The risk for depression markedly rises during the 5-6 years leading up to the cessation of menstruation, known as the menopause transition. Exposure to extreme estradiol levels may help explain this increase but few studies have examined individual sensitivity to estradiol in predicting perimenopausal depression.
Method: The current study recruited 101 perimenopausal women.