Health care expenditures and therapeutic outcomes of a pharmacist-managed anticoagulation service versus usual medical care.

Study Objective: To evaluate the differences in health care expenditures and therapeutic outcomes of patients receiving warfarin therapy management by a pharmacist-managed anticoagulation service compared with those receiving warfarin management by usual medical care.

Design: Retrospective, matched-cohort study.

Data Source: University of Pittsburgh Medical Center (UPMC) and UPMC Health Plan.

Association between the tumor necrosis factor locus and the clinical outcome of Leishmania chagasi infection.

A periurban outbreak of visceral leishmaniasis (VL) caused by the protozoan Leishmania chagasi is ongoing outside Natal, northeast Brazil. Manifestations range from asymptomatic infection to disseminated visceral disease. Literature reports suggest that both genetic and environmental factors influence the outcome of infection.