Publications by authors named "Bethany Deariove"
Article Synopsis
- The study investigates how certain genetic features of SARS-CoV-2 might make the virus resistant to the Ad26.COV2.S vaccine, which had an overall efficacy of 56% in preventing moderate to severe COVID-19.
- Data from 484 vaccinated and 1,067 placebo participants revealed that the vaccine was less effective against the Lambda variant, particularly in regions like Latin America where the virus's genetic diversity was high.
- The research also found that vaccine efficacy decreased with genetic differences between the virus and the vaccine strain, particularly at specific amino acid positions and based on the virus’s neutralization resistance level.
