gene predicts clinical recovery after sustained virological response in decompensated hepatitis C cirrhosis.

Background: Patients with decompensated hepatitis C virus (HCV) cirrhosis experience various outcomes after sustained virological response (SVR), ranging from clinical recovery to further deterioration. We hypothesised that the genetic risk for steatosis, namely the polymorphisms rs738409 of Patatin-like Phospholipase Domain-Containing 3 (), rs58542926 of Transmembrane-6-Superfamily-2 (), and rs641738 of Membrane-bound O-acyltransferase Domain-Containing 7 (), is predictive of recovery.

Methods: We prospectively enrolled 56 patients with Child-Pugh (CPT) B/C cirrhosis who underwent antiviral therapy.

Differences between rat strains in models of retinopathy of prematurity.

Purpose: Genetic factors appear to modulate the incidence and severity of retinopathy of prematurity (ROP). Different rat strains may be analogous to genetic differences across human ethnic groups. We investigated the incidence and severity of neovascularization (NV) in Brown Norway (BN) and Sprague Dawley (SD) rats in oxygen-induced retinopathy (OIR) and acidosis-induced retinopathy (AIR) models for ROP.