CSF HIV escape is a recently recognised phenomenon that suggests that despite suppressive treatment, HIV RNA may be detected in the CNS compartment in some individuals. In rare cases this is associated with clinical neurological disease, while in most cases, neurological consequences are not apparent. Attempts at characterising the biological substrates of CSF escape and further investigating the neurological consequences need to be made to better understand the implications of this condition for the HIV cure agenda as well as for clinical outcomes.
View Article and Find Full Text PDFTwo experiments were conducted to examine differences between people with Prader-Willi syndrome and an obese comparison group in choosing a larger quantity of food delivered after a delay (15, 30, or 60 seconds) or a small quantity of food delivered immediately. Individuals with Prader-Willi syndrome selected the larger food quantity. Choices by the obese comparison group tended to be equally divided between both options.
View Article and Find Full Text PDFSince its inception, the John F. Kennedy Center has attempted to overcome developmental problems, which create restrictive barriers to the participation of individuals with specific disabilities in our broader society. Some of Nicholas Hobbs's earliest efforts involved developing strategies for preventing children's emotional and behavior problems, which interfered with their later full participation in society.
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