Publications by authors named "Betelihim Haile"
Am J Transplant
November 2022
Article Synopsis
- Respiratory viral infections (RVI) in lung transplant recipients (LTRs) can lead to chronic lung allograft dysfunction (CLAD), and elevated levels of donor-derived cell-free DNA (%ddcfDNA) during RVI may predict CLAD progression.
- A study involving 39 LTRs tracked %ddcfDNA and lung function over one year, finding that high %ddcfDNA correlated with significantly greater declines in lung function and increased rates of progression or failure compared to those with low levels.
- The findings suggest that measuring %ddcfDNA at the time of RVI is a more reliable indicator of how well LTRs will recover lung function, compared to traditional histopathology assessments.
