Homeostatic Functions of Tissue-Resident Macrophages and Their Role in Tissue Maintenance.

Tissue-resident macrophages are best known for their indispensable role in immunological reactions, where they contribute to immune defense and resolution of inflammation. However, recent studies have also uncovered that they provide crucial tissue-specific functions that support organ homeostasis and maintenance. Accordingly, defects in macrophage function or development can disrupt the delicate balance of organ homeostasis, leading to pathological conditions.

-Specific IgA Secretion in the Female Reproductive Tract Induced via Per-Oral Immunization Confers Protection against Primary Challenge.

is an obligate intracellular pathogen that causes sexually transmitted disease. In women, chlamydial infections may cause pelvic inflammatory disease (PID), ectopic pregnancy, and infertility. The role of antibodies in protection against a primary infection is unclear and was a focus of this work.