[Left ventricular aneurysmectomy: technical evolution and results].

A critical review of surgical techniques for left ventricular aneurysm treatment, with reference to literature data and author's personal experience, is reported. Aneurysm plicatio, performed in 35 patients, was always associated to coronary artery bypass graft and carried out mainly in small aneurysms of the posterior wall. In the last years this technique has been used very rarely, due to papillary muscle damage risk.

Pharmacokinetics of cefonicid in serum and its penetration into lung tissue, bronchial mucosa and pleura.

Cefonicid pharmacokinetics in serum and tissue penetration into the lung parenchyma, bronchial mucosa and pleura were studied in 39 patients undergoing lung excision for malignancy. Cefonicid concentrations in serum and tissues samples were assayed at different times after a single 1 g intramuscular administration. The concentrations observed were much higher than the reported minimal inhibitory concentrations for the microorganisms commonly responsible for bronchial and pulmonary infections and therapeutic concentrations were still detectable in the tissues 24 h after dosing.

[Role and limits of diagnostic imaging in the staging of lung cancer].

A total of 474 histologically proved Lung Cancers (LC) were evaluated by Conventional Radiology (CR) and Computed Tomography (CT) in order to assess the role of these two diagnostic modalities in the staging of LC. In 196/474 LC it was possible also to refer, for the evaluation of the diagnostic reliability, to the surgical control. The CR features of LC both at stage III (13% of the global series) and at stage I-peripheral T1 (16% of the global series) presented very high positive and negative predictive values (90% and 95%, retrospectively); in these cases it was considered useless to perform CT.

[Prosthetic pathology of mechanical and biological valves in the mitral and aortic position. II. Hemodynamic-angiographic evaluation and anatomo-surgical aspects].

The catheterization parameters of 42 patients with surgically confirmed prosthetic valve malfunction were retrospectively analyzed in order to evaluate the role of hemodynamic and angiocardiographic examination in the diagnosis of prosthetic complications. The invasive investigation provided in all cases more precise informations regarding the type and grade of prosthetic malfunction as compared to noninvasive techniques. Transvalvular gradients could be quantified, the amount of regurgitation could be defined and associated lesions (paraprosthetic aneurysms, aortic root dissection, fistulas secondary to bacterial endocarditis) could be recognized.

[Coronary aneurysm. Report of a case of inflammatory etiology and review of the literature (author's transl)].

The case is presented of a 31 year old man with anteroseptal myocardial infarction, whose chest X-ray showed an anomalous protrusion along the left cardiac border. After 6 months, the increase in size of such protrusion lead to left ventriculographic and coronariographic examination: the presence of a large nonfistulous bisaccular coronary aneurysm was documented along the anterior descending branch of the left coronary artery. Cardiac surgery consisted in resection of the coronary aneurysm and of the left ventricular post-infarction area, and was followed by good surgical and angiocardiographic result.

[Surgical treatment of postinfarctual left ventricular aneurysm (author's transl)].

Ventricular aneurysm is a frequent complication of myocardial infarction, but its diagnostic and prognostic implications are not fully defined. A surgical series of 66 ventricular resections for symptomatic left ventricular aneurysm is analyzed. Pts.

[Surgical complications of pacemaker implantation (author's transl)].

During the period 1966-1977, 705 pacemaker implantations with transvenous endocardial electrode and 369 substitutions of generators were carried out, besides 275 operations treating some complications after implantation were required. The most frequent complications were: endocardial electrode dislocation (9.4%), lesion caused by decubitus (7.

[Bypass aorto-coronarico. Correlazione tra dati clinici, emodinamici ed angiografici e risultato operatorio in 100 casi (author's transl)].

In 100 consecutive patients, subjected to myocardial revascularization by aorto-coronary saphenous vein bypass grafting with a standard technique, several clinical, hemodynamic and angiographic data were studied in correlation with the short-term prognosis. The operative mortality (6% on the whole) appeared to be strictly correlated with the degree of left ventricular impairment. Among the considered hemodynamic indices (LVEDP, CI, EDV, EF), EF was the most significant one: mortality was 0% if EF was normal, but raised to 15 and 40% respectively, when this was moderately or severely reduced.