The study of antiarrhythmic medications in infancy (SAMIS): a multicenter, randomized controlled trial comparing the efficacy and safety of digoxin versus propranolol for prophylaxis of supraventricular tachycardia in infants.

Background: Supraventricular tachycardia (SVT) is one of the most common conditions requiring emergent cardiac care in children, yet its management has never been subjected to a randomized controlled clinical trial. The purpose of this study was to compare the efficacy and safety of the 2 most commonly used medications for antiarrhythmic prophylaxis of SVT in infants: digoxin and propranolol.

Methods And Results: This was a randomized, double-blind, multicenter study of infants <4 months with SVT (atrioventricular reciprocating tachycardia or atrioventricular nodal reentrant tachycardia), excluding Wolff-Parkinson-White, comparing digoxin with propranolol.

Successful stent treatment of pulmonary vein stenosis following atrial fibrillation radiofrequency ablation.

Pulmonary vein stenosis is a known complication of radiofrequency ablation of atrial fibrillation foci. We report a case of severe unilateral pulmonary vein stenosis following radiofrequency ablation resulting in no perfusion to the right lung. Simple balloon dilation was unsuccessful in this patient.