Publications by authors named "BertinTchombou Hig-Zounet"
J Virol Methods
January 2024
Article Synopsis
- ASPCR is a cost-effective method for detecting HIV-1 drug resistance mutations, showing potential for use in resource-limited settings.
- In a study involving 44 HIV-1 plasma samples from patients in Chad, ASPCR demonstrated strong correlation with Sanger sequencing for detecting six major drug resistance mutations, with R values over 0.97 and desirable threshold differences for most mutations.
- While ASPCR showed high reproducibility and improved detection rates for multiple mutations, the detection of the K70R mutation was less effective compared to other mutations, highlighting areas for refinement in this diagnostic approach.
