Innovative Method for the Analysis of Dexpanthenol in Hair Care Products.

Dexpanthenol is a widely used humectant in hair care products, especially anti-hairfall products. The hair care industry is highly regulated in East Asia and treats products containing the combination of dexpanthenol, zinc pyrithione, and nicotinamide (vitamin B₃) as quasi-drugs. Because dexpanthenol lacks a UV chromophore, existing methodologies for analysis in finished products include pretreatments and/or HPLC-UV analysis at low wavelengths at which poor signal-to-noise is observed.

Liquid Chromatography Method for the Simultaneous Quantification of Biotin and Vitamin B12 in Vitamin B Supplements.

The determination of cyanocobalamin (vitamin B12) and biotin has always been challenging because of the lack of a chromophore for biotin and trace level input for vitamin B12 in supplements. Microbiological assay methods are currently used for quantitation. However, these methods are time consuming, may lack specificity, and have high imprecision.

Cyclodextrins as complexation and extraction agents for pesticides from contaminated soil.

The binding constants of seven commonly used pesticides (2,4-D, acetochlor, alachlor, dicamba, dimethenamid, metolachlor, and propanil) with native and derivatized cyclodextrins (α-CD, β-CD, γ-CD, hydroxypropyl-β-CD, methyl-β-CD, sulfated-β-CD, and carboxymethyl-β-CD) were measured using affinity capillary electrophoresis. All cyclodextrins showed significant binding interactions with each of the seven pesticides investigated, with the exception of sulfated-β-CD which exhibited negligible binding to acetochlor, alachlor, and metolachlor. Propanil was found to bind most strongly to the cyclodextrins in this study.