Ischemic Stroke During Dengue Infection: A Report of 2 Cases.

BACKGROUND Involvement of the central nervous system during infection with dengue virus (DENV) is recognized. However, ischemic stroke is rarely reported. Herein are described 2 cases of patients with ischemic stroke in which DENV infection was demonstrated.

Decomposition of socioeconomic inequalities in arboviral diseases in Brazil and Colombia (2007-2017).

Background: We used surveillance data from Brazil and Colombia during 2007-2017 to assess the presence of socioeconomic inequalities on dengue, chikungunya and Zika at the neighborhood level in two Latin American cities.

Methods: To quantify the inequality, we estimated and decomposed the relative concentration index of inequality (RCI) accounting for the spatiotemporal distribution of the diseases.

Results: There were 281 426 arboviral cases notified in Fortaleza, Brazil, and 40 889 in Medellin, Colombia.

Spatiotemporal distribution and socioeconomic disparities of dengue, chikungunya and Zika in two Latin American cities from 2007 to 2017.

Objective: To assess the presence, pattern and magnitude of socioeconomic inequalities on dengue, chikungunya and Zika in Latin America, accounting for their spatiotemporal distribution.

Methods: Using longitudinal surveillance data (reported arboviruses) from Fortaleza, Brazil and Medellin, Colombia (2007-2017), we fit Bayesian hierarchical models with structured random effects to estimate: (i) spatiotemporally adjusted incidence rates; (ii) Relative Concentration Index and Absolute Concentration Index of inequality; (iii) temporal trends in RCIs; and (iv) socioeconomic-specific estimates of disease distribution. The spatial analysis was conducted at the neighbourhood level (urban settings).

Importance of clinical and laboratory characteristics in the diagnosis of dengue and chikungunya co-infection: Probable case report.

We report the case of a 38-year-old woman who initially consulted for an undifferentiated fever. Although her clinical condition evolved with signs and symptoms compatible with dengue with alarm signs and that the anti-dengue IgM detection in a single sample indicated it was a probable case that could have happened during the previous three months, the patient kept consulting due to little improvement. On the tenth day after the onset of symptoms, she presented with painful polyarticular symmetric edema, as well as hyperpigmented lesions in the nasolabial fold.

Single-Nucleotide Polymorphisms in NOD1, RIPK2, MICB, PLCE1, TNF, and IKBKE Genes Associated with Symptomatic Dengue in Children from Colombia.

Functional immunological evidence supports the impact that the host genetic variability has on the susceptibility to develop asymptomatic or symptomatic dengue infection. Children are more prone to develop severe dengue. Thus, we have evaluated possible associations between single-nucleotide polymorphisms (SNPs) located in immune genes and the development of symptomatic dengue in children from two Colombian populations with differences in genetic backgrounds and geographical features.

[Variants in the TNFA, IL6 and IFNG genes are associated with the dengue severity in a sample from Colombian population].

Introduction: The genetic makeup of the host contributes to the clinical profile of dengue. This could be due to the effect of variants in the genes encoding pro-inflammatory cytokines.

Objective: To evaluate the association between the variants of three polymorphisms in TNFA, IL6 and IFNG candidate genes with dengue severity in a sample of Colombian population.

[Dengue infection: A common cause of febrile syndrome in patients from Quibdó, Chocó, Colombia].

Introduction: Quibdó, a municipality in Chocó, has poor public services and weather and social conditions that favor dengue transmission. However, there are few studies about this problem in this district.

Objective: To determine the frequency of dengue infection in patients with acute febrile syndrome and to compare clinical features among dengue infected patients with other febrile diseases.

African genetic ancestry is associated with a protective effect on Dengue severity in colombian populations.

The wide variation in severity displayed during Dengue Virus (DENV) infection may be influenced by host susceptibility. In several epidemiological approaches, differences in disease outcomes have been found between some ethnic groups, suggesting that human genetic background has an important role in disease severity. In the Caribbean, It has been reported that populations of African descent present considerable less frequency of severe forms compared with Mestizo and White self-reported groups.

Frequency and clinical manifestations of dengue in urban medellin, Colombia.

A dengue fever surveillance study was conducted at three medical facilities located in the low-income district of San Javier in Medellin, Colombia. During March 2008 to 2009, 781 patients with fever regardless of chief complaint were recruited for acute dengue virus infection testing. Of the 781 tested, 73 (9.

Frequency and clinical features of dengue infection in a schoolchildren cohort from medellin, Colombia.

To determine the incidence of dengue infection, we established active surveillance of febrile episodes in a cohort of schoolchildren from three schools in Medellin, Colombia. We followed a cohort of 2,379 schoolchildren in 2010 and followed 1,840 of these children the following year. During the follow-up time, 264 schoolchildren displayed 297 febrile episodes; of these, 23 episodes (7.

[Serum platelet-activating factor acetylhydrolase activity in dengue patients of African or mestizo descendency].

Introduction: Severe dengue infection is characterized by enhanced vascular permeability produced by cytokines and biochemical mediators. One of these mediators is the platelet-activating factor. Degradation of platelet-activating factor is accomplished by its specific acetylhydrolase.

Serum levels of interleukin-6, tumor necrosis factor-alpha and interferon-gamma in infants with and without dengue.

This study compared the serum levels of IL-6, TNF-alpha and IFN-gamma, in children under 1 year of age with and without dengue. Sera were collected from a total of 41 children living in the Department of Antioquia, Colombia (27 patients with dengue and 14 controls). The results showed higher cytokine levels in children with dengue than without dengue, with statistically significant differences for IL-6 and IFN-gamma.

[Nutritional status of indigenous children aged up to six years in the Embera-Katio Indian reserve in Tierralta, Cordoba, Colombia].

Introduction: Knowledge of the nutritional state of the children is an valuable indicator of the general state of development in an entire population.

Objective: The prevalence of malnutrition was determined in Embera-Katio's indigenous children, aged 0-6 years, and associated factors associated with malnutrition were identified.

Materials And Methods: A cross-sectional study was undertaken in the Resguardo Embera-Katío, in Tierralta in the Province of Cordoba, located in northern Colombia.

[The clinical behavior of dengue in patients hospitalized in the Antonio Roldán Betancur Hospital of Apartadó, Antioquia, 2000].

Introduction: Dengue has exhibited an epidemic behaviour in Apartad6 since 1998.

Objective: To describe the clinical behavior of dengue in patients hospitalized with this diagnosis in the Antonio Roldán Betancur Hospital of Apartadó in the year 2000.

Materials And Methods: Descriptive retrospective study with variables obtained from clinical records of patients hospitalized with dengue in the Antonio Roldán Betancur Hospital of Apartadó.