Publications by authors named "Bert M Celie"
Article Synopsis
- Unexplained abnormal fatigue is chronic fatigue lasting over six months without a clear medical cause, and twelve individuals were studied to investigate potential underlying issues.
- The study utilized near-infrared spectroscopy to analyze handgrip tests and identified four participants with abnormal oxygen extraction patterns, indicating possible mitochondrial myopathy.
- Further analyses revealed various mitochondrial abnormalities and mutations in three of these four individuals, suggesting that near-infrared spectroscopy could help identify a specific subgroup of people with mitochondrial dysfunction among those suffering from unexplained fatigue.
The influence of subcutaneous adipose tissue (ATT) and oxygen (O2) delivery has been poorly defined in frequency domain (FD) near-infrared spectroscopy (NIRS). Therefore, the aim of this study was to investigate the possible influence of these variables on all FD NIRS responses using a reliable protocol. Moreover, these influences were also investigated when using relative oxy- and deoxyhemoglobin and -myoglobin (oxy[Hb + Mb] and deoxy[Hb + Mb]) values (in %).
View Article and Find Full Text PDFThe purpose of this paper is to test whether peripheral oxygenation responses measured with near-infrared spectroscopy (NIRS) would differ between patients suffering from mitochondrial myopathy (MM) and healthy controls during an incremental handgrip exercise test. Two groups of subjects were studied: 11 patients with MM and 11 age- and gender-matched untrained healthy controls. A handgrip exercise until exhaustion protocol was used consisting of 2 min periods of work (½ Hz) at different intensities, separated by a 60 s rest period.
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