Effects of Walnut Bark Extract on the Human Platelet Aggregation, Adhesion, and Plasmatic Coagulation In Vitro.

Thrombosis is the formation of a clot within a blood vessel. Antithrombotic drugs are used for treating thrombosis, which can be the cause of hemorrhage. Currently, there is a need to discover novel antithrombotic drugs.

Phytochemical Profile and Antioxidant Activity of L Growing in Morocco.

Background: L (NS) is a powerful antioxidant and medicinal plant with many therapeutic applications particularly in traditional medicine for respiratory, gastrointestinal, rheumatic, and inflammatory disorders, as well as cancer.

Objective: The aim of this study is to extract the active ingredients from the Moroccan L and determine its antioxidant properties. We hypothesize that the separation of the compounds from L has either a positive or negative effect on antioxidants.

Origanum majorana L. extract exhibit positive cooperative effects on the main mechanisms involved in acute infectious diarrhea.

Ethnopharmacological Relevance: Origanum majorana L. (Lamiaceae) is commonly used in Moroccan folk medicine to treat infantile colic, abdominal discomfort and diarrhea. Liquid stools and abdominal discomfort observed in acute infectious diarrhea are the consequences of imbalance between intestinal water secretion and absorption in the lumen, and relaxation of smooth muscle surrounding the intestinal mucosa.

Myorelaxant Activity of essential oil from Origanum majorana L. on rat and rabbit.

Ethnopharmacological Relevance: Origanum majorana L. (Lamiaceae) was usually used in Moroccan folk medicine to treat infantile colic and abdominal discomfort.

Materials And Methods: The essential oil from the aerial part of the dry Origanum majorana L.

Effects of Root Bark Extract on Platelet Aggregation, Bleeding Time, and Plasmatic Coagulation: and Experiments.

Platelets have an important role in thrombosis and haemostasis. Hyperactivity of the platelets has been associated with thromboembolic diseases and represents the main cause of complications of cardiovascular diseases. Crude aqueous extract (CAE) of root bark was evaluated for bleeding time, antiaggregant activity by using agonists, thrombin, ADP, collagen, or arachidonic acid ( and ), and anticoagulant activity by measuring the clotting parameters: activated partial thromboplastin time, prothrombin time, thrombin time, and fibrinogen dosage ( and ).

Natural product based composite for extraction of arsenic (III) from waste water.

Natural based composites of hydroxyapatite/Gum Arabic designed for removal of toxic metal arsenic (III) from waste water were synthesized and evaluated. Several composites with various compositions were prepared by the wet chemical method and analyzed using various spectroscopic and analytical methods such as: Fourier transform infrared spectroscopy, total organic carbon production, XRD analysis and scanning electron microscope. The rates of weight loss and water absorption of the HAp/GA composites as a function of time were evaluated in phosphate-buffered saline solution at 37 °C and a pH of 7.

Preparation and characterization of biodegradable nanocomposites derived from carboxymethyl cellulose and hydroxyapatite.

Development of a cost-effective technology for extraction and quantification of carcinogenic and toxic organic materials which are widely used in the industry are critical to humans. Membrane technology received much attention and has already been widely used in this area. In this work, we offer a newly developed bio-based nanocomposite membrane for removal of bisphenol-A (BPA) from water.

Chemical composition, vasorelaxant, antioxidant and antiplatelet effects of essential oil of Artemisia campestris L. from Oriental Morocco.

Background: Artemisia campestris L. (Asteraceae) is a medicinal herb traditionally used to treat hypertension and many other diseases. Hence, this study is aimed to analyze the essential oil of A.

Structure and properties of hydroxyapatite/hydroxyethyl cellulose acetate composite films.

The main aim of this research work was to develop a new inorganic-organic film. Hydroxyapaptite (HAp) particles that represent the inorganic phase was mixed well with hydroxyethyl cellulose acetate (HECA), which representing the organic phase and then the inorganic-organic films were fabricated by evaporating of the solvent. The structure as well as the properties of the formed films were characterized using different analytical tools such as field emission scanning electron microscopy (FEG-SEM), thermo-gravimetric analysis (TGA), Fourier transform infra-red (FT-IR) spectroscopy.

Synthesis and characterization of composite based on cellulose acetate and hydroxyapatite application to the absorption of harmful substances.

The aim of this work is to develop composite materials with hydroxyapatite (HAp) mineral and organic matrix such as cellulosic polymers. We use cellulose acetate with different percentages, and then inorganic-organic films were fabricated by evaporation of solvent. The composite films were characterized using emission scanning electron microscopy (FEG-SEM), thermo-gravimetric analysis (TGA) and Fourier transform infra-red (FT-IR) spectra.

Flavonoids purified from parsley inhibit human blood platelet aggregation and adhesion to collagen under flow.

Introduction: Blood platelets are directly involved in both haemostatic and pathologic thrombotic processes, through their adhesion, secretion and aggregation. In this study, we investigated the effect of genins (aglycone flavonoids without sugar group) isolated from parsley (Petroselinum crispum) leaves in vitro on human platelet aggregation and adhesion to a collagen-coated surface under physiologic flow conditions.

Materials And Methods: The aggregation and adhesion studies were monitored after pre-incubation of platelets with genins.

Effect of essential oil of Anthemis mauritiana Maire & Sennen flowers on intestinal smooth muscle contractility.

The aim of the present study is to determine the chemical composition of the essential oil extracted from the flowers of Anthemis mauritiana Maire & Sennen (EOAM) and to investigate its antispasmodic effects on intestinal smooth muscle. The phytochemical composition was revealed by gas chromatography-mass spectrometer. Eighteen compounds were identified representing 90.

Aminoglutethimide included in nanocapsules suspension: comparison of GC-MS and HPLC methods for control.

Gas chromatography-mass spectrometry (GC-MS) and high performance liquid chromatography (HPLC) offer highly efficient and potentially sensitive separation and detection techniques. This work describes the quantification of aminoglutethimide (AG) in nanocapsules suspension with both techniques. The analysis of different lots containing known concentrations of drug (1, 2, 3 and 4 mg ml(-1)) were used to investigate the quantitative capabilities of both chromatographic techniques.

GC-MS determination of phenobarbitone entrapped in poly-epsilon-caprolactone nanocapsules.

In order to evaluate the concentration of a hydrophilic drug, phenobarbitone, in a suspension of poly-epsilon-caprolactone nanocapsules, a gas chromatographic-mass spectrometric procedure, performed after methylation of the drug, was developed and validated. Free phenobarbitone (in solution in the liquid phase), released phenobarbitone (after opening the nanocapsules with ethyl acetate) and total entrapped phenobarbitone (after extraction with methylene chloride), were measured. Experimental results for four lots with various concentrations showed that the highest preparation of entrapped drug (80%) was obtained for a total concentration of 3.