Publications by authors named "Bernd Dreyer"
Article Synopsis
- Life evolved in a reducing environment but faced challenges from reactive oxygen species (ROS) during the great oxidation event (GOE), leading to the development of copper-zinc superoxide dismutases (CuZnSODs) in some plants.
- The chemical inhibitor lung cancer screen 1 (LCS-1) was used to study the effects of CuZnSOD inhibition on plant growth, transcription, and metabolism across different species, including bryophytes and vascular plants.
- The results showed that LCS-1 caused oxidative stress and a core physiological response related to glutathione balance in all species, but varying metabolic responses were observed based on the number and types of CuZnSOD isoforms present in each plant.
In animals, endocytosis of a seven-transmembrane GPCR is mediated by arrestins to propagate or arrest cytoplasmic G protein-mediated signaling, depending on the bias of the receptor or ligand, which determines how much one transduction pathway is used compared to another. In , GPCRs are not required for G protein-coupled signaling because the heterotrimeric G protein complex spontaneously exchanges nucleotide. Instead, the seven-transmembrane protein AtRGS1 modulates G protein signaling through ligand-dependent endocytosis, which initiates derepression of signaling without the involvement of canonical arrestins.
View Article and Find Full Text PDFPlants continuously need to adapt to their environment and prioritize either growth or defense responses to secure survival and reproduction. Trade-offs between growth and defense are often attributed to the allocation of energy for growth to adaptation responses. Still, the exact mechanisms underlying growth and defense trade-offs are poorly understood.
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