Publications by authors named "Bernardo Martinez-Miguel"

Background: Respiratory viruses have clinical and epidemiological importance. With the COVID-19 pandemic, interest has focused on SARS-CoV-2, but as a result, the number of samples available for the differential diagnosis of other respiratory viruses has increased.

Study Design: Cross-sectional study.

View Article and Find Full Text PDF

Background: Risk factors for severe dengue manifestations have been attributed to various factors, including specific serotypes, sex, and age. Mexico has seen the re-emergence of DENV-3, which has not circulated in a decade.

Objective: To describe dengue serotypes by age, sex, and their association with disease severity in dengue-positive serum samples from epidemiological surveillance system units.

View Article and Find Full Text PDF
Article Synopsis
  • Limited studies exist on how the oral microbiome affects SARS-CoV-2 infection and disease severity.
  • The research analyzed saliva samples from 31 asymptomatic individuals, 176 mild cases, 57 hospitalized severe patients, and 18 fatal cases to assess microbiome differences.
  • The findings showed significant changes in saliva microbiota diversity and composition related to disease severity, suggesting a potential link between oral bacteria and COVID-19 outcomes, which could inform prognosis and understanding of the disease's pathogenesis.
View Article and Find Full Text PDF

In this study, we analyzed the sequences of SARS-CoV-2 isolates of the Delta variant in Mexico, which has completely replaced other previously circulating variants in the country due to its transmission advantage. Among all the Delta sublineages that were detected, 81.5 % were classified as AY.

View Article and Find Full Text PDF

Background: Associations between vitamin D (VD) deficiency and the risk of SARS-CoV-2 infection have been documented in cross-sectional population studies. Intervention studies in patients with moderate to severe COVID-19 have failed to consistently document a beneficial effect.

Objective: To determine the efficacy and safety of VD-supplementation in the prevention of SARS-CoV-2 infection in highly exposed individuals.

View Article and Find Full Text PDF

Background Zika, dengue and chikungunya viruses (ZIKV, CHIKV and DENV) are temporally associated with neurological diseases, such as Guillain-Barré syndrome (GBS). Because these three arboviruses coexist in Mexico, the frequency and severity of GBS could theoretically increase. This study aims to determine the association between these arboviruses and GBS in a Mexican population and to establish the clinical characteristics of the patients, including the severity of the infection.

View Article and Find Full Text PDF

Purpose: Rituximab [chimeric anti-CD20 monoclonal antibody], alone or combined with chemotherapy, is used in the treatment of non-Hodgkin's lymphoma (NHL). Rituximab binds to CD20 and inhibits intracellular survival/growth pathways leading to chemo/immunosensitization of tumor cells in vitro. The contribution of rituximab Fc-FcR interaction in signaling is not known.

View Article and Find Full Text PDF