Publications by authors named "Bernardo Brito Palma"
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Synopsis of recent research by authors named "Bernardo Brito Palma"
Bernardo Brito Palma's research focuses on the interactions and functions of cytochrome P450 enzymes and their associated redox partners, particularly the role of cytochrome P450 oxidoreductase (CPR) and cytochrome b5 in electron transfer and biotransformation processes.
His studies employ high-throughput systems to investigate the genotoxic potential of cytochrome P450-mediated metabolism, exploring how genetic variations in human CYP1A2 can influence susceptibility to chemical carcinogenesis.
Palma's work also examines the reactivity of small heterocycles like oxetanes as alkylating agents, evaluating their potential risks and applications, particularly in drug safety and the creation of new materials for technology.