Publications by authors named "Bernard C G Sabbe"

Psychotic depression is a frequent, severe psychiatric condition in older depressive inpatients aged 60 years and older. Older adults with a psychotic depression exhibit specific symptoms that are different from those in younger adults with psychotic depression. Moreover, the symptoms are also different from those in older adults  with a major depression without psychotic features.

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Article Synopsis
  • The study looked at how the Maudsley Staging Method (MSM) can help predict how well electroconvulsive therapy (ECT) works for adults with severe depression.
  • Researchers tested 73 patients undergoing ECT to see how their depression improved after treatment, using a specific rating scale.
  • They found that longer episodes of depression and more severe symptoms meant lower chances of getting better, suggesting that the MSM can help doctors decide on treatments more effectively.
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Objective: To explore the correlations between observer ratings and instrumental parameters across domains of psychomotor functioning in depression.

Method: In total, 73 patients with major depressive disorder underwent extensive psychomotor and clinical testing. Psychomotor functioning was assessed with (i) an observer-rated scale (the CORE measure) and also objectively with (ii) 24-h actigraphy, and (iii) a fine motor drawing task.

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Background: Electroconvulsive therapy (ECT) is considered to be the most effective treatment in severe major depression. The identification of reliable predictors of ECT response could contribute to a more targeted patient selection and consequently increased ECT response rates. Aims To investigate the predictive value of age, depression severity, psychotic and melancholic features for ECT response and remission in major depression.

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