Publications by authors named "Bernard Belhassen"

Article Synopsis
  • * AAs were the first symptom of IAS in 52% of patients, and nearly a quarter had multiple AAs documented.
  • * The study found a moderate incidence of severe outcomes, including a yearly primary endpoint rate of 1.4%, with younger patients experiencing higher risks and other complications affecting some patients as well.
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  • - A 37-year-old male athlete experienced abnormal heart rhythms during exercise, but no prior structural heart disease was found.
  • - Tests revealed that invasive programmed ventricular stimulation triggered ventricular fibrillation, and a mutation in the CASQ2 gene was identified.
  • - This case suggests that individuals with CASQ2-related polymorphic ventricular tachycardia may have heightened ventricular excitability during such stimulation.
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  • - The text discusses Calcium Release Deficiency Syndrome (CRDS), a serious genetic heart condition that can cause sudden cardiac arrest without clear reasons and is not detectable through standard tests.
  • - The study aimed to analyze electrocardiogram (ECG) responses after brief periods of fast heart rates followed by pauses in order to develop a diagnostic test for CRDS.
  • - Findings showed that patients with CRDS had a significantly greater change in T-wave amplitude on their ECG after a pause compared to control groups, indicating a potential diagnostic marker for this syndrome.
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  • There is limited understanding of how idiopathic ventricular fibrillation (IVF) starts, but previous research suggests that it usually doesn't depend on pauses in heart rhythm.
  • The study aimed to investigate the initiation patterns of polymorphic ventricular tachycardia (PVT) in IVF patients, analyzing a total of 410 arrhythmia episodes among 180 patients.
  • Results showed that about 27.2% of PVT episodes were pause-dependent, with the majority occurring during normal heart rhythms and initiating PVCs mostly having short coupling intervals (under 350 ms).
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  • The study examines the impact of left bundle branch block (LBBB) on the QRS frontal plane axis after transcatheter aortic valve replacement (TAVR) in patients with normal baseline QRS duration.
  • Out of 720 patients, 141 developed new LBBB post-TAVR, with most experiencing a significant leftward shift in their QRS axis.
  • Patients showing a rightward or no axis shift had a higher likelihood of developing high degree atrioventricular block (AVB) compared to those with a leftward shift, indicating a potential risk factor in LBBB post-TAVR.
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Article Synopsis
  • Diagnosing concealed nodo-ventricular (cNV) and concealed His-ventricular (cHV) pathways in tachyarrhythmias is complex, and the study presents new observations to improve diagnosis.* -
  • The research involved seven cases that highlighted key lab tests such as differential ventricular overdrive pacing, responses to specific premature ventricular complexes, and the effects of adenosine on tachycardia identification.* -
  • The findings reveal that these concealed pathways can exhibit diverse clinical symptoms, and specific diagnostic techniques can help distinguish between cNV and cHV pathway-mediated arrhythmias.*
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  • The study investigates whether the baseline R-wave amplitude in the V1 ECG lead can predict the risk of high-degree atrioventricular block (AVB) after transcatheter aortic valve replacement (TAVR) in patients with normal QRS duration.
  • Out of 720 patients who underwent TAVR, 141 developed left bundle branch block (LBBB), with 14 of those experiencing high-degree AVB requiring pacemaker implantation.
  • The findings indicate that a smaller R-wave amplitude in the V1 lead is associated with a higher risk of developing high-degree AVB, suggesting it could be a useful predictor for clinicians.
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Article Synopsis
  • The study investigates patients with right bundle branch block (RBBB)-ventricular tachycardia (VT) and arrhythmogenic cardiomyopathy (ACM) by examining ECG characteristics of sinus rhythm (SR) and VT.
  • It included 70 patients, revealing that the most common sites of origin for the VTs were primarily in the inferior and lateral walls of the left ventricle (LV), with a good correlation to electro-anatomic mapping (EAM) data.
  • The findings highlight frequent abnormalities in SR depolarization and repolarization, which are associated with clinical implications in patients with ACM and RBBB-VT.
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