Publications by authors named "Bernard Barzilay"
Article Synopsis
- Non-invasive cardiac output monitoring using electrical biosensing technology (EBT) allows for continuous monitoring of hemodynamic variables in neonates, helping to identify instability early for potential interventions.
- The use of thoracic (TEBT) and whole body (WBEBT) monitoring methods has grown in neonatology, although TEBT is not a reliable measure of cardiac output, it may track changes in individual patients over time.
- Recommendations suggest avoiding WBEBT for cardiac output monitoring and highlight the need for further research to address variations in technology and methodology before EBT can become routine in clinical practice.
Article Synopsis
- An international survey was conducted across 560 neonatal intensive care units (NICUs) in 24 European countries to assess the usage of lung ultrasound (LU), revealing significant variability in adoption rates (20%-98%).
- Most NICUs (76%) use LU for clinical reasons, primarily to diagnose respiratory issues and manage acute conditions.
- Key barriers to LU implementation include lack of experience in technical skills and image interpretation, with suggestions for improvement involving specific training courses and a standardized international guideline.
The use of point of care ultrasound to assess cardiovascular function performed by a neonatologist who is not a cardiologist, is gaining interest in the neonatal intensive care unit (NICU). Clinical signs such as heart rate, blood pressure and capillary refill time provide limited insight into the adequacy of systemic blood flow and organ perfusion. Functional echocardiography (echo) enables real time evaluation of cardiac performance, identifying the nature of cardiovascular compromise, guiding therapeutic decisions and monitoring response to treatment.
View Article and Find Full Text PDFBackground: Most studies have revealed that the incidence of morbidity and mortality of preterm male infants is greater than that of preterm female infants. Recently, conflicting outcomes have been reported regarding mixed-gender twins. The aim of this study was to estimate the association between gender and outcome in newborn twins of different gender.
View Article and Find Full Text PDFWe describe a congenital mass in the nasopharynx of an infant presenting with dyspnea and feeding difficulties. Magnetic resonance imaging demonstrated 2 separate polypoid nasal cavity masses that were endoscopically resected. Histologically, both lesions were composed of mature adipose tissue with broad fibrous bands and several foci of brown fat.
View Article and Find Full Text PDFBackground: Diagnosis of late onset sepsis (LOS) in very low birth weight (VLBW) preterm infants relies mainly on clinical suspicion, whereas prognosis depends on early initiation of antibiotic treatment. RALIS is a mathematical algorithm for early detection of LOS incorporating six vital signs measured every 2 hours.
Objective: The aim of this study is to study RALIS ability to detect LOS before clinical suspicion.
Pharmacokinetics of oral ibuprofen for patent ductus arteriosus closure in preterm infants.
Arch Dis Child Fetal Neonatal Ed
March 2012
Background: Oral ibuprofen has been shown to be associated with excellent patent ductus arteriosus (PDA) closure rates and a favourable safety profile, but limited data exist regarding its pharmacokinetics in preterm infants.
Objective: To evaluate pharmacokinetic parameters of oral ibuprofen in preterm infants.
Methods: Plasma ibuprofen levels were determined at various time points, and pharmacokinetic profiles were calculated after a single dose of 10 mg/kg of oral ibuprofen.
Background: Vasa previa is a rare condition associated with neonatal morbidity and mortality that may be diagnosed prenatally using transvaginal sonography. The aim of this study was to assess the prenatal detection of vasa previa and its subsequent impact on neonatal outcomes in two 10-year periods (1988-1997 versus 1998-2007).
Method: Retrospective review of all cases of vasa previa.
Objective: Primary bone and soft-tissue tumors occur rarely in pregnancy. The objective of this study was to describe the outcome of a large cohort of pregnant patients with these rare tumors.
Methods: Pregnant women diagnosed with bone or soft-tissue tumors during pregnancy or within 3 months after delivery were identified retrospectively for the years 1983-2003 in the University Health Network database, University of Toronto.
Aim: To investigate glutathione and antioxidant status changes in erythrocytes from febrile children receiving repeated supratherapeutic paracetamol doses.
Methods: Fifty-one children aged 2 months to 10 years participated in the study. Three groups were studied: group 1 (n = 24) included afebrile children who did not receive paracetamol; and groups 2 (n = 13) and 3 (n = 14) included children who had fever above 38.
Colonization rate of bacteria in the throat of healthy infants.
Int J Pediatr Otorhinolaryngol
March 2002
Objective: the human throat is a major ecological site for various bacteria that can reach neighbouring sterile sites and cause mild infections or invasive diseases. The aim of this study was to investigate the carriage rate of several potential pathogens in the throat of healthy children under the age of 2 years.
Methods: cultures were taken from the tonsils of 1000 healthy infants aged 1-24 months attending well-baby clinics, who had not received antibiotic therapy during the preceding 14 days.