Publications by authors named "Berkelhammer C"

Article Synopsis
  • A new multitarget stool DNA test was developed to enhance colorectal cancer screening by improving specificity and assessing both DNA markers and hemoglobin levels.
  • In a study involving over 20,000 adults aged 40 and older undergoing screening colonoscopy, the test’s sensitivity for colorectal cancer was found to be 93.9% and its specificity for identifying advanced neoplasia was 90.6%.
  • Compared to a standard fecal immunochemical test (FIT), the multitarget test showed significantly higher sensitivity for detecting colorectal cancer and advanced precancerous lesions, although the FIT had slightly better specificity for advanced neoplasia.
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Colonic leiomyomas are rare. Their clinical presentation ranges from asymptomatic polyps detected on endoscopy to large symptomatic abdominopelvic masses. Imaging findings are usually non-specific, and percutaneous biopsy might help with differential diagnosis.

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 Drug-induced liver injury is a common cause of transaminitis, occurring in up to 5% of patients who are hospitalized for liver failure. In pregnancy, transaminitis is seen in conditions which may require expedited delivery.  A 39-year-old G2P0010 at 27 weeks' gestation with chronic hypertension on labetalol was found to have elevated transaminases.

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Intramural duodenal hematoma (IDH) is an extremely rare complication after endoscopic biopsy. It typically presents with symptoms due to duodenal obstruction, which include abdominal pain and bilious vomiting. The hematoma may also expand and cause ampullary compression leading to pancreatitis and cholestasis.

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Germline mutations in the BRCA-1 associated tumor protein 1 (BAP1) increase susceptibility to mesothelioma and other cancers. We describe a patient with a family history of peritoneal mesothelioma, who developed malignant peritoneal mesothelioma at age 45 in the absence of known asbestos exposure. These findings lead us to hypothesize that the mesothelioma occurred in the setting of germline a BAP1 mutation.

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Background: Little information exists to guide monitoring and treatment of malnourishment during pregnancy after bariatric surgery. Here we present a case with severe deficiencies and recommendations for testing and treatment.

Case: Our patient underwent a duodenal switch procedure resulting in significant weight loss and numerous deficiencies.

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Purulent skeletal muscle abscesses can occur in Crohn's disease. We report a case of a sterile seroma complicating percutaneous drainage of a purulent skeletal muscle abscess in Crohn's ileitis. We compare and contrast this case with a similar case we published earlier.

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Clopidogrel is a commonly prescribed antiplatelet agent that carries a rare risk of hepatotoxicity. We describe a case of severe clopidogrel-induced hepatitis with liver biopsy assessment. Prompt recognition and withdrawal of the offending agent are imperative to prevent progression and potentially fatal liver injury.

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Antihistamine-induced hepatitis is rare. We present 2 cases of antihistamine-induced hepatitis with autoimmune features, caused by loratidine. One case was confirmed by rechallenge.

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