Publications by authors named "Berjan Demirtas"
The effect of hydrophilic statins on adiponectin, leptin, visfatin, and vaspin levels in streptozocin-induced diabetic rats.
Naunyn Schmiedebergs Arch Pharmacol
October 2024
Article Synopsis
- The study aimed to evaluate the impact of hydrophilic statins (pravastatin and rosuvastatin) on adipokine levels and glucose metabolism in diabetic rats.
- Diabetic rats treated with pravastatin showed improvements in body weight and fasting blood glucose levels, along with increased adiponectin and vaspin, while rosuvastatin did not significantly impact these factors.
- Overall, pravastatin was found to be more effective than rosuvastatin in improving metabolic parameters in diabetic rats, suggesting its beneficial role in glucose regulation.
Acute carbon monoxide (CO) poisoning may cause liver damage and liver dysfunction. Therefore, in this study, we aimed to compare the efficiency of normobaric oxygen (NBO) and high-flow nasal cannula oxygen (HFNCO) treatments on liver injury. For that purpose, 28 male Wistar albino rats were divided into four groups (Control, CO, CO + NBO, and CO + HFNCO).
View Article and Find Full Text PDFStatin treatment may increase the risk of diabetes; there is insufficient data on how statins affect glucose regulation and glycemic control and the effects of statins on liver enzymes related to carbohydrate metabolism have not been fully studied. Therefore, we aimed to compare the effects of the statin derivatives, pravastatin, and rosuvastatin, on carbohydrate metabolism in an experimental diabetic rat model. Female Wistar albino rats were used and diabetes was induced by intraperitoneal injection of streptozotocin.
View Article and Find Full Text PDFThis study was aimed to assess oxidative stress, pro-inflammatory cytokines and some trace elements in healthy pet cats exposed to environmental tobacco smoke. Forty healthy cats were included in this study. Cats were divided in two groups: Exposed to tobacco smoke (ETS; n = 20) and non-exposed to tobacco smoke (NETS; n = 20).
View Article and Find Full Text PDFIn the present study, coumarin and some coumarin derivatives (esculetin, scoparone, and 4-methylumbelliferone) were investigated for their lipid-lowering effect in rats. Male Sprague-Dawley rats (150-200 g) were divided into six groups and each group comprised of five rats. Hepatic injury-dependent hyperlipidemia was induced by carbon tetrachloride (CCl, 1.
View Article and Find Full Text PDF