Morphology of the Ovaries in Condition of Inhalation Intoxication with Dust-Saline Aerosols of the Aral Sea in Female White Rats.

Background: After some clinical studies of the reproductive health of the female population of the Aral Sea region, we concluded that it is necessary to confirm by experiment the theory of the direct influence of dust-saline aerosols of the Aral Sea on the reproductive system of female individuals.

Aim: The purpose of this work is to study the effect of dust-saline aerosols of the Aral Sea on the folliculogenesis process in rats at inhalation intoxication.

Methods: Inhalation in rats was carried out for 30 days for 4 hours a day for 5 days a week in special inoculating cylindrical chambers with the extra-chamber placement of animals in individual boxes and dynamic aerosol delivery.

Comparative Assessment of Women's Reproductive Health in the Areas Bordering With the Aral Sea Region.

Aim: We examined 435 women of Aktobe region and 328 women of South Kazakhstan region, living in areas bordering the Aral Sea region during the study and comparative assessment of the impact of climatic and anthropogenic factors of Aral region on the reproductive health of the female population.

Material And Methods: The survey based on the comprehensive clinical-functional and laboratory studies accounting the regional and environmental ecological factors. Survey subject was the area of 2 settlements of Aktobe region and 1 settlement of South Kazakhstan region.

The Study of Cellular and Molecular Physiological Characteristics of Sperm in Men Living in the Aral Sea Region.

Background: Extreme environmental situation in the Aral crisis has caused a massive chemical pollution of the territory for decades with high doses of pesticides, herbicides. Discharge of industrial waste into the rivers that feed the Aral Sea has lead to the development of various pathological processes in the human body, as well as disruption of reproductive function in young men.

Aim: To evaluate the performance of molecular cellular changes in the sperm of men under the influence of dust and salt aerosols in Aral Sea region.

Disturbance of Antioxidant Enzymes and Purine Metabolism in the Ejaculate of Men Living in Disadvantaged Areas of Kyzylorda Region.

Aim: Objective of the study was to evaluate the state of the main indicators of antioxidant status and enzymes of purine metabolism in the germ cells of men living in the zone of ecological catastrophe Aral Sea region.

Methods: The criterion for inclusion is the stay of an adult in the Aral Sea area is not less than 5 years, employment in occupations with no more than 2 hazard class. Determination of the activity of adenosine deaminase (ADA) was conducted in semen by the method of Nemechek et al.

The Health Status of the Reproductive System in Women Living In the Aral Sea Region.

In order to assess women's reproductive health in the Kyzylorda region (the Aral Sea) of Kazakhstan, 1406 women were involved in an integrated clinical-functional and laboratory examination, given regional and environmental ecological factors. The high level of endocrine gynecological pathology is indicated in the examined women. In both examined zones, there is a late menarche over 16 years old, which is 39%.