The perioperative use of inhaled prostacyclins in cardiac surgery: a systematic review and meta-analysis.

Purpose: Perioperative pulmonary hypertension (PH) is an independent risk factor for morbidity and mortality in cardiac surgery. While inhaled prostacyclins (iPGIs) are an established treatment of chronic PH, data on the efficacy of iPGIs in perioperative PH are scarce.

Methods: We searched PubMed, Embase, the Web of Science, CENTRAL, and the grey literature from inception until April 2021.

High turnover for ambulatory orthopedic surgery.

Purpose Of Review: The trend in the perioperative management of patients having orthopedic surgery in the ambulatory setting emphasizes time-efficiency and rapid turnovers. Anesthetic techniques and management continue to evolve to increase efficiency and decrease time spent in recovery.

Recent Findings: Minimizing time patients spend in phase 1 recovery or bypassing phase 1 altogether, known as fast-tracking, has become an important goal in containing costs in high turnover, ambulatory settings.

Vascular activation is a strong predictor of mortality in coronavirus disease 2019 patients on the ICU.

Respiratory failure in coronavirus disease 2019 (COVID-19) patients is one of the most frequent causes for referral to the ICU. A significant percentage of these patients does not survive the infection due to thromboembolic complications. Furthermore, the vascular system seems also to be involved in the pathogenesis.

Association between postoperative delirium and postoperative cerebral oxygen desaturation in older patients after cardiac surgery.

Background: Near-infrared spectroscopy non-invasively measures regional cerebral oxygen saturation. Intraoperative cerebral desaturations have been associated with worse neurological outcomes. We investigated whether perioperative cerebral desaturations are associated with postoperative delirium in older patients after cardiac surgery.