Aims: Gouty arthritis is a frequent and disabling complication in heart failure patients. This study aimed to investigate which factors are associated with the occurrence of gouty arthritis in these patients.
Methods And Results: A case-control study was performed in heart failure patients (February 2007 to October 2009).
Objective: To systematically review the literature investigating the relationship between use of diuretics and the risk of gouty arthritis.
Methods: PubMed (1950-October 2009), Embase (1974-October 2009), and the Cochrane Library (up to October 2009) were searched using keywords and MeSH terms diuretics, adverse effects, and gout. For this review, the technique of "best evidence synthesis" was used.