Publications by authors named "Berdikulov M"

Bovine anaplasmosis is an infectious vector-borne disease caused by bacteria of the genus , which have a wide global distribution and represent a high economic burden for agriculture. The use of molecular genetic techniques has increased our knowledge of the species diversity of spp. and naturally susceptible animals.

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Background And Aim: infection in cattle causes major economic losses in livestock production in many Central Asian countries, including the southern region of Kazakhstan. This study aimed to obtain a recombinant surface protein (TaSP) and to investigate its possible use as an antigen in an indirect enzyme-linked immunosorbent assay (ELISA) for the serological diagnosis of bovine theileriosis.

Materials And Methods: Recombinant TaSP was obtained by cloning a polymorphic region of the TaSP gene, expressing it in strain BL21, and purifying it by metal chelating chromatography.

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Background: The camel pox virus (CMLV) is a widespread infectious viral disease of camels. It is necessary to conduct research on new strains for the development of vaccines.

Aim: The research aims to characterize a novel strain isolated from the CMLV used to produce a CMLV vaccine.

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Foot-and-mouth disease (FMD) has historically caused far-reaching economic losses to many regions worldwide. FMD control has been problematic, and the disease is still prevalent in many West and Central Asia countries. Here, we review the progress made by Kazakhstan in achieving freedom from FMD and discuss some of the challenges associated with maintaining the FMD-free status, as evidenced by the occurrence of an outbreak in 2022.

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Foot-and-mouth disease (FMD) has long been recognized as a highly contagious, transboundary disease of livestock incurring substantial losses and burdens to animal production and trade across Africa, the Middle East, and Asia. Due to the recent emergence of the O/ME-SA/Ind-2001 lineage globally contributing to the expansion of FMD, molecular epidemiological investigations help in tracing the evolution of foot-and-mouth disease virus (FMDV) across endemic and newly affected regions. In this work, our phylogenetic analysis reveals that the recent FMDV incursions in Russia, Mongolia, and Kazakhstan in 2021-2022 were due to the virus belonging to the O/ME-SA/Ind-2001e sublineage, belonging to the cluster from Cambodian FMDV isolates.

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Central Asia, including Kazakhstan, is an endemic area of Theileria and Babesia infections in cattle. Current data on the geographic distribution, prevalence, and genetic diversity of these pathogens in vertebrate hosts are lacking in Kazakhstan. The present study aimed to fill this gap, using molecular techniques for the first time.

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Brucellosis is one of the most important and widespread bacterial zoonoses worldwide. Cases are reported annually across the range of known infectious species of the genus Globally, , primarily hosted by domestic sheep and goats, affects large proportions of livestock herds, and frequently spills over into humans. While some species, such as , are well controlled in livestock in areas of North America, the Greater Yellowstone Ecosystem supports the species in native wild ungulates with occasional spillover to livestock.

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Article Synopsis
  • In autumn 2020, Kazakhstan experienced significant poultry die-offs due to avian influenza, starting in the north and spreading to eleven provinces throughout the country.
  • Researchers collected samples from affected birds and used RT-PCR for initial virus detection, followed by full-genome sequencing of the A/H5N8 subtype identified in the outbreaks.
  • Phylogenetic analysis revealed that these viruses are closely related to isolates from Russia and Eastern Europe, indicating that the A/H5N8 subtype likely arrived in Kazakhstan via migratory birds, posing ongoing risks to local poultry populations.
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