Publications by authors named "Berat Ebik"
This article discusses infection, a zoonotic parasite that lives in the liver bile ducts. A 31-year-old female patient was diagnosed with symptoms such as nausea, increased liver enzymes, and right upper quadrant pain for about a year. The parasite was detected in the common bile duct by Endoscopic Ultrasound (EUS) and removed by Endoscopic Retrograde Cholangio Pancreatography (ERCP).
View Article and Find Full Text PDFHistological Findings in Antigen E Positive and Negative in Chronic Hepatitis B.
J Coll Physicians Surg Pak
August 2024
Objective: To determine the histopathological findings in patients with HBeAg-positive chronic HBV infection (immunotolerant phase in old terminology) and HBeAg-negative chronic HBV infection (inactive carrier phase in old terminology).
Study Design: Observational study. Place and Duration of the Study: Department of Gastroenterology, University of Health Sciences, Diyarbakir Gazi Yasargil Education and Research Hospital, Diyarbakir, Turkiye and Diyarbakir and Mersin University School of Medicine, Diyarbakir, Turkiye, from May 2014 to August 2022.
Did diet compliance and remission reduce oxidative stress in celiac patients?
Rev Assoc Med Bras (1992)
May 2024
Objective: We aimed to examine the effect of remission status on thiol-disulfide homeostasis in celiac patients and thus to indirectly determine the effect of oxidative stress and inflammation caused by non-compliance with the diet.
Methods: Between February 2019 and December 2021, 117 patients diagnosed with celiac disease were included in this prospective randomized and controlled study. In addition to routine tests of celiac patients, thiol and disulfide measurements were made from the blood both at the beginning of the study and at the end of the first year.
Article Synopsis
- - The study aimed to explore the incidence of celiac disease (CD) in patients diagnosed with microscopic colitis (MC) and to differentiate the characteristics of both conditions.
- - The research involved 90 MC patients and found that only 1.1% had CD, with minimal positivity for various autoantibodies, indicating a low correlation between the two diseases.
- - Notably, an increase in intraepithelial lymphocytes (IEL) was identified in MC patients who did not respond to treatment, but overall, the study did not support the idea that CD is more prevalent among MC patients.
In this study, we evaluated the relation between the presence of lymphopenia and the need of intensive care unit (ICU) or mortality. A total of 1670 COVID-19 patients were divided according to the severity of lymphopenia developing at the time of COVID-19 infection. According to the symptoms and need of ICU, the infection was classified as mild or severe.
View Article and Find Full Text PDFDo oral antiviral drugs used in the treatment of chronic hepatitis B cause erectile dysfunction?
Eur J Gastroenterol Hepatol
February 2024
Objective: The effect of antiviral drugs on the erectile dysfunction (ED) problem expressed by some patients using antiviral drugs due to chronic hepatitis B infection (HBV) was investigated.
Methods: A total of 102 male patients receiving antiviral therapy for HBVinfection without any known non-cirrhotic and comorbid disease that may cause ED and whodon't use any drugs with an ED formation potential were analyzed through the InternationalIndex of Erectile Function test.
Results: Among the patients admitted to the study, anxiety disorder was detected as 24.
What does quantitative HBsAg level mean in chronic hepatitis D infection?
Eur J Gastroenterol Hepatol
March 2023
Article Synopsis
- The study investigated the link between serum HBsAg levels and liver fibrosis in patients with chronic hepatitis delta virus (HDV) infection.
- It included 98 patients (53 noncirrhotic, 45 cirrhotic) and found significant correlations between HBsAg levels, HDV RNA, and liver enzymes, especially in noncirrhotic individuals.
- The researchers concluded that quantitative HBsAg levels could serve as useful indicators of viral activity and histological changes in noncirrhotic HDV patients, aiding in chronic infection management.
Article Synopsis
- This study aimed to understand the long-term gastrointestinal effects and gut-brain interaction disorders in patients hospitalized for COVID-19 compared to those without the infection.
- The analysis included data from 883 patients, revealing that gastrointestinal symptoms were more prevalent in COVID-19 patients during hospitalization, but by the 12-month follow-up, controls reported higher rates of constipation and hard stools.
- Additionally, COVID-19 patients showed a significantly higher prevalence of irritable bowel syndrome (IBS) compared to controls, with certain factors like allergies and medication usage being associated with IBS diagnosis.
Relationship Among , Lower Esophagus Sphincter Pressure, and Gastroesophageal Reflux: A Single-Center Experience.
Sisli Etfal Hastan Tip Bul
September 2022
Objectives: The aim of the study was to evaluate the relationship among lower esophageal sphincter pressure (LESP), (Hp), and gastroesophageal reflux (GER).
Methods: The retrospective study included patients with isolated hypertensive or hypotensive lower esophageal sphincter (LES) who underwent esophageal manometry in our gastroenterology motility laboratory and had normal manometry results. Demographic characteristics, complaints on admission, upper endoscopy findings, 24-h esophageal pH monitoring results, and presence of Hp in gastric biopsy were evaluated.
What does the Procalcitonin Level Tell us in Patients with Acute Pancreatitis?
J Coll Physicians Surg Pak
October 2022
Article Synopsis
- The study aims to identify factors influencing procalcitonin (PCT) levels and their connection to the severity of acute pancreatitis (AP) in patients.
- Conducted in Turkey between April 2017 and June 2021, the research involved 214 AP patients and analyzed their PCT and CRP levels within the first 12 hours of admission.
- Results revealed that higher PCT levels were significantly associated with severe pancreatitis; PCT showed good sensitivity for predicting severity, especially in cases of concurrent infections.
Background And Aim: Several studies have suggested that treatment with direct-acting antivirals (DAAs) in patients with chronic hepatitis C virus (HCV) may be associated with an increased risk of developing hepatocellular carcinoma (HCC). We investigated the incidence and risk factors of HCC in HCV patients who achieved a sustained virologic response (SVR) following DAA therapies.
Materials And Methods: The medical data of patients who were diagnosed with HCV and received DAA therapy in two tertiary centers in Turkey were retrospectively collected.
Background: Data regarding outcome of Coronavirus disease 2019 (COVID-19) in vaccinated patients with autoimmune hepatitis (AIH) are lacking. We evaluated the outcome of COVID-19 in AIH patients who received at least one dose of Pfizer- BioNTech (BNT162b2), Moderna (mRNA-1273) or AstraZeneca (ChAdOx1-S) vaccine.
Patients And Methods: We performed a retrospective study on AIH patients with COVID-19.
Oxidative stress and the importance of eradication in patients with functional dyspepsia.
Saudi J Gastroenterol
December 2022
Background: To investigage the thiol and disulphide levels in Helicobacter pylori-positive patients with non-ulcer dyspepsia and investigate the change in these levels with eradication therapy.
Methods: This is a prospective observational study. A total of 320 patients diagnosed with dyspepsia according to Rome IV criteria were included in the study.
Background And Aims: A few case reports of autoimmune hepatitis-like liver injury have been reported after severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccination. We evaluated clinical features, treatment response and outcomes of liver injury following SARS-CoV-2 vaccination in a large case series.
Approach And Results: We collected data from cases in 18 countries.
Background: Viral infections can cause acute pancreatitis. Idiopathic pancreatitis has an important proportion in the etiology of acute pancreatitis.
Objective: To investigate the rate of development of acute pancreatitis (AP) in COVID-19 patients and to determine the rate of idiopathic pancreatitis in the etiology of this pancreatitis.
Background: We investigated associations between baseline use of immunosuppressive drugs and severity of Coronavirus Disease 2019 (COVID-19) in autoimmune hepatitis (AIH).
Patients And Methods: Data of AIH patients with laboratory confirmed COVID-19 were retrospectively collected from 15 countries. The outcomes of AIH patients who were on immunosuppression at the time of COVID-19 were compared to patients who were not on AIH medication.
Article Synopsis
- A study examined the prevalence of gastrointestinal (GI) symptoms in hospitalized COVID-19 patients compared to non-COVID patients, confirming that GI symptoms are more common in those with COVID-19 (59.7% vs. 43.2%).
- The study involved 2036 patients and used a specific questionnaire to assess GI symptoms at hospital admission and after one month.
- Key findings include a reduction in GI symptoms over time in COVID-19 patients, but persistent nausea was associated with factors like female sex, high body mass index, dyspnea, and elevated C-reactive protein levels.
Object: We aimed to evaluate the elevation of amylase and lipase enzymes in coronavirus disease 2019 (COVID-19) patients and their relationship with the severity of COVID-19.
Method: In this study, 1378 patients with COVID-19 infection were included. Relation of elevated amylase and lipase levels and comorbidities with the severity of COVID-19 was analysed.
Background And Aims: Data regarding outcome of COVID-19 in patients with autoimmune hepatitis (AIH) are lacking.
Approach And Results: We performed a retrospective study on patients with AIH and COVID-19 from 34 centers in Europe and the Americas. We analyzed factors associated with severe COVID-19 outcomes, defined as the need for mechanical ventilation, intensive care admission, and/or death.
Isotretinoin is a first-generation retinoid initially approved for the treatment of severe cases of acne vulgaris (nodulocystic acne). Because of its broad anti-inflammatory and immunomodulatory properties, it has been used beyond its initial approval in a myriad of other indications. Adverse effects of isotretinoin vary from xerosis to teratogenicity.
View Article and Find Full Text PDFBiliary Fasciola gigantica case report from Turkey.
Southeast Asian J Trop Med Public Health
May 2011
We present a case of Fasciola gigantica-induced biliary obstruction and cholestasis diagnosed and treated via endoscopy and trichlorobendazole treatment. This is the first case of Fasciola gigantica treated via endoscopic biliary extraction during ERCP and drug treatment reported from Turkey.
View Article and Find Full Text PDFA case of Fasciola gigantica-induced biliary obstruction and cholestasis is reported in Turkey. The patient was a 37- year-old woman, and suffered from icterus, ascites, and pain in her right upper abdominal region. A total of 7 living adult flukes were recovered during endoscopic retrograde cholangiopancreatography (ERCP).
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